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sc291

Generic: HIP-modified allogeneic CD19-directed CAR T cell

sc291: developed by 1 company · 2 clinical trials tracked.

sc291 evidence translation

What we can confirm

What it means

Source-backed records connect sc291 to SANA; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could sc291 → SANA affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence3 indications · 0 study sponsors

Related indications

Non Hodgkin Lymphoma; Lupus ErythematosusChronic Lymphocytic LeukemiaSystemic Lupus Erythematosus

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
Sana Biotechnology, Inc. (SANA)
Non Hodgkin Lymphoma; Lupus Erythematosus
Phase 1
Clinical Trials (2)

A Phase 1 Study Evaluating SC291, a Hypoimmune, Allogeneic CD19-directed CAR T Cell Therapy, in Subjects With Severe Relapsed or Refractory Autoimmune Diseases (GLEAM)

NCT06294236·Phase 1·SANA
Active, not recruiting

Primary endpoint: Evaluate safety and tolerability of SC291

Interventionalopen7 targetStarted 2024-04Completion 2028-035 sites · United StatesSana Biotechnology

A Phase 1 Study Evaluating SC291, a Hypoimmune, Allogeneic CD19-directed CAR T Cell Therapy, in Relapsed and/or Refractory B-cell Malignancies (ARDENT)

NCT05878184·Phase 1·SANA
Active, not recruiting

Primary endpoint: Evaluate safety and tolerability of SC291

Interventionalopen16 enrolledStarted 2023-05Completion 2038-1110 sites · Australia, United StatesSana Biotechnology

Frequently asked questions

Who is developing sc291?

sc291 is being developed by Sana Biotechnology, Inc..

How many clinical trials involve sc291?

BioSniper tracks 2 clinical trials involving sc291.