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sc291

Generic: HIP-modified allogeneic CD19-directed CAR T cell

sc291: sourced relationships with 1 company · 2 clinical trials tracked.

sc291 evidence translation

What we can confirm

What it means

Source-backed records connect sc291 to SANA; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could sc291 → SANA affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence3 indications · 0 study sponsors

Related indications

Non Hodgkin Lymphoma; Lupus ErythematosusChronic Lymphocytic LeukemiaSystemic Lupus Erythematosus

Study sponsors

No additional listed-company sponsor is linked.

Dated Pipeline Records (1)
CompanyDated record stage
Sana Biotechnology, Inc. (SANA)
developer · Reported 2024-02-29 · Current development: unknownSource
Non Hodgkin Lymphoma; Lupus Erythematosus
Phase 1
Clinical Trial Registry Records (2)

A Phase 1 Study Evaluating SC291, a Hypoimmune, Allogeneic CD19-directed CAR T Cell Therapy, in Subjects With Severe Relapsed or Refractory Autoimmune Diseases (GLEAM)

NCT06294236Registry updated 2025-11-25·Phase 1·SANA
Active, not recruiting

Primary endpoint: Evaluate safety and tolerability of SC291

Interventionalopen7 targetStarted 2024-04Completion 2028-035 sites · United StatesSana Biotechnology

A Phase 1 Study Evaluating SC291, a Hypoimmune, Allogeneic CD19-directed CAR T Cell Therapy, in Relapsed and/or Refractory B-cell Malignancies (ARDENT)

NCT05878184Registry updated 2025-10-02·Phase 1·SANA
Active, not recruiting

Primary endpoint: Evaluate safety and tolerability of SC291

Interventionalopen16 enrolledStarted 2023-05Completion 2038-1110 sites · Australia, United StatesSana Biotechnology

Frequently asked questions

Which companies have sourced relationships with sc291?

sc291 has dated SEC/FDA relationship records for Sana Biotechnology, Inc..

How many clinical trials involve sc291?

BioSniper tracks 2 clinical trials involving sc291.