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safusidenib

safusidenib: developed by 1 company · 3 clinical trials tracked.

safusidenib evidence translation

What we can confirm

3 tracked trials

What it means

Source-backed records connect safusidenib to NUVB; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could safusidenib → NUVB affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence3 indications · 0 study sponsors

Related indications

Grade 2 IDH1-mutant Glioma; Grade 2 Glioma (Astrocytoma or Oligodendroglioma) With an IDH1 Mutation; GliomaGliomaOligodendroglioma

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
Nuvation Bio Inc. (NUVB)
Grade 2 IDH1-mutant Glioma; Grade 2 Glioma (Astrocytoma or O…
Phase 3
Clinical Trials (3)

A Phase 2, Multicenter, Clinical Study to Evaluate the Efficacy and Safety of Safusidenib Erbumine in Participants With Isocitrate Dehydrogenase 1 (IDH1)-Mutant Glioma Who Discontinued Vorasidenib Treatment Due to Progressive Disease

NCT07703436·Phase 2·NUVB
Not yet recruiting

Primary endpoint: Objective Response Rate (ORR) per modified Response Assessment in Neuro-Oncology (RANO) 2.0 assessed by Blinded Independent Central Review (BICR)

Interventionalopen40 targetStarted 2027-03Completion 2032-037 sites · United StatesNuvation Bio Inc.

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Safusidenib in Participants With Grade 2 Isocitrate Dehydrogenase 1 (IDH1)-Mutant Glioma

NCT07712757·Phase 3·NUVB
Not yet recruiting

Primary endpoint: Progression Free Survival (PFS) assessed by Blinded Independent Central Review (BICR) per modified Response Assessment in Neuro-Oncology (RANO) 2.0

InterventionalRandomizedquadruple140 targetStarted 2027-03Completion 2032-03Nuvation Bio Inc.

A Phase 3, Multicenter, Clinical Study to Evaluate the Efficacy and Safety of Safusidenib Erbumine in Participants With Isocitrate Dehydrogenase 1 (IDH1)-Mutant Glioma

NCT05303519·Phase 3·NUVB
Recruiting

Primary endpoint: Part 1: Incidence of adverse events (AEs) and serious adverse events (SAEs)

InterventionalRandomizedquadruple365 targetStarted 2023-06Completion 2030-1250 sites · Australia, United StatesNuvation Bio Inc.

Frequently asked questions

Who is developing safusidenib?

safusidenib is being developed by Nuvation Bio Inc..

How many clinical trials involve safusidenib?

BioSniper tracks 3 clinical trials involving safusidenib.