rp2
rp2: developed by 1 company · 5 clinical trials tracked.
rp2 evidence translation
What we can confirm
5 tracked trials
What it means
What to watch
Prepared research question
How could rp2 → REPL affect its developer, and what evidence supports the link?
Traceable citations · Unknowns marked
See linked entities and source evidence4 indications · 0 study sponsors
Related indications
Study sponsors
No additional listed-company sponsor is linked.
Development Pipeline (1)
| Company | Phase |
|---|---|
| Replimune Group, Inc. (REPL) Hepatocellular Carcinoma; Gastric Adenocarcinoma; Cancer | Phase 1 |
Clinical Trials (5)
Phase II Study of Neoadjuvant RP2 in Combination With Preoperative Flot for Patients With Stage II or Higher, Non-metastatic Gastroesophageal Adenocarcinoma
Primary endpoint: Pathologic complete response
A Randomized, Phase 2/3, Open-Label Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab Versus Ipilimumab in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma
Primary endpoint: Overall Survival (OS)
A Phase 2, Open-label, Multicenter Study Investigating RP2 Oncolytic Immunotherapy in Combination With Second-line Therapy in Patients With Locally Advanced Unresectable, Recurrent and/or Metastatic Hepatocellular Carcinoma
Primary endpoint: Overall Response Rate per modified RECIST 1.1
A Phase 2 Clinical Trial Investigating Oncolytic Immunotherapy in Combination With Atezolizumab and Bevacizumab for the Treatment of Patients With Advanced Microsatellite Stable and Mismatch Repair Proficient Colorectal Carcinoma
Primary endpoint: Objective Response Rate (ORR)
An Open-Label, Multicenter, Phase 1 Study of RP2 as a Single Agent and in Combination With PD1 Blockade in Patients With Solid Tumors
Primary endpoint: Percentage of adverse events (AEs)
Frequently asked questions
Who is developing rp2?
rp2 is being developed by Replimune Group, Inc..
How many clinical trials involve rp2?
BioSniper tracks 5 clinical trials involving rp2.