romosozumab
romosozumab: 4 clinical trials tracked.
romosozumab evidence translation
What we can confirm
4 tracked trials
What it means
What to watch
Prepared research question
What is verified about romosozumab, and what remains unknown?
Traceable citations · Unknowns marked
See linked entities and source evidence2 indications · 1 study sponsors
Related indications
Study sponsors
Clinical Trial Registry Records (4)
A Phase 1, Open-label, Randomized, Parallel Group Study to Evaluate the Relative Bioavailability of Romosozumab (AMG 785) 210 mg Administered as a Single SC Injection or 2 SC Injections in Healthy Participants
Primary endpoint: Area Under the Concentration-time Curve From Time 0 Extrapolated to Infinity (AUCinf) of romosozumab
Investigating the Efficacy of Romosozumab in Augmenting Bone Density and Muscle Mass to Enhance the Outcomes of Spine Surgery
Primary endpoint: Change in Hounsfield Units (HU) at L1 Vertebra
A Phase 3, Open-Label, Multicenter, Randomized Study to Evaluate Efficacy and Safety of Romosozumab Compared With Bisphosphonates in Children and Adolescents With Osteogenesis Imperfecta
Primary endpoint: Number of Clinical Fractures
Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI
Primary endpoint: Change in vBMD at the Distal Femur, measured by pQCT after 12 months of romosozumab treatment