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romiplostim

Generic: romiplostim·Brand: Nplate

romiplostim: developed by 1 company · 4 clinical trials tracked · 1 FDA decision.

romiplostim evidence translation

What we can confirm

1 FDA record · 4 tracked trials

What it means

Source-backed records connect romiplostim to AMGN; that link alone does not prove the drug works.

What to watch

Watch active trials and any change in FDA or trial status.
BioSniper AIPage evidence connected

Prepared research question

How could romiplostim → AMGN affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence4 indications · 0 study sponsors

Related indications

Primary Immune Thrombocytopenia; Chemotherapy-induced ThrombocytopeniaMyelofibrosisPrimary Immune ThrombocytopeniaThrombocytopenia

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
AMGEN INC (AMGN)
Primary Immune Thrombocytopenia; Chemotherapy-induced Thromb…
Phase 3
Clinical Trials (4)

A Phase 3, Randomized, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of Romiplostim Plus Predniso(lo)ne vs. Predniso(lo)ne Alone for the Treatment of Adults With Previously Untreated Primary Immune Thrombocytopenia (ITP).

NCT07700238·Phase 3·AMGN
Not yet recruiting

Primary endpoint: Percentage of Participants With a Durable Platelet Response (DPR)

InterventionalRandomizedopen126 targetStarted 2026-07Completion 2029-09Amgen

High Dose Ruxolitinib and Allogeneic Stem Cell Transplantation in Myelofibrosis Patients With Splenomegaly

NCT06345495·Phase 2
Recruiting

Primary endpoint: Safety and adverse events (AEs)

Interventionalopen30 targetStarted 2024-10Completion 2029-011 site · United StatesM.D. Anderson Cancer Center

Romiplostim for Prevention of Severe Chemotherapy Induced Thrombocytopenia in Lymphoma Patients - Phase II Study

NCT04673266·Phase 2
Completed

Primary endpoint: measure of incidence of indication for dose delays

Interventionalopen11 enrolledStarted 2020-12Completion 2026-047 sites · United StatesMemorial Sloan Kettering Cancer Center

PROCLAIM: A Phase 3 Randomized Placebo-controlled Double-blind Study of Romiplostim for the Treatment of Chemotherapy-induced Thrombocytopenia in Patients Receiving Chemotherapy for Treatment of Non-small Cell Lung Cancer (NSCLC), Ovarian Cancer, or Breast Cancer

NCT03937154·Phase 3·AMGN
Active, not recruiting

Primary endpoint: Incidence of either a chemotherapy dose delay or reduction

InterventionalRandomizedquadruple145 targetStarted 2020-02Completion 2027-0250 sites · Argentina, Austria, Brazil, Bulgaria…Amgen
FDA Decisions1 records
Approval1 INDICATIONS AND USAGE Nplate is a thrombopoietin receptor agonist indicated for the treatment of thrombocytopenia in: Adult patients with immune thrombocytopenia (ITP) who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy. ( 1.1 ) Pediatric patients 1 year of age and older with ITP for at least 6 months who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy. ( 1.1 ) Nplate is indicated to increase survival in adults and in (AMGN)FDA ↗
BLA125268Type 1 - New Molecular EntityOrphan DrugPrioritySubcutaneousInjectable

Frequently asked questions

Who is developing romiplostim?

romiplostim is being developed by AMGEN INC.

How many clinical trials involve romiplostim?

BioSniper tracks 4 clinical trials involving romiplostim.

What is romiplostim's latest FDA decision?

The most recent tracked FDA decision for romiplostim is Approval for 1 INDICATIONS AND USAGE Nplate is a thrombopoietin receptor agonist indicated for the treatment of thrombocytopenia in: Adult patients with immune thrombocytopenia (ITP) who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy. ( 1.1 ) Pediatric patients 1 year of age and older with ITP for at least 6 months who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy. ( 1.1 ) Nplate is indicated to increase survival in adults and in , dated August 22, 2008.