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ridinilazole

Generic: Ridinilazole

ridinilazole: 4 clinical trials tracked.

ridinilazole evidence translation

What we can confirm

4 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

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Watch trial status, endpoints, and the next source-backed update.
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Prepared research question

What is verified about ridinilazole, and what remains unknown?

Run cited research

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See linked entities and source evidence1 indications · 1 study sponsors
Clinical Trials (4)

A Randomized, Double Blind, Active Controlled Study to Evaluate the Safety and Tolerability of Ridinilazole Compared With Vancomycin and to Assess the Pharmacokinetics of Ridinilazole in Adolescent Subjects (Aged 12 to <18 Years) With Clostridioides Difficile Infection

NCT04802837·Phase 3·SMMT
Terminated

Primary endpoint: Incidence and Severity of Treatment-emergant Adverse Events

InterventionalRandomizedquadruple2 targetStarted 2021-05Completion 2022-0918 sites · United StatesSummit Therapeutics

A Phase 3, Randomized, Double-blind, Active Controlled Study to Compare the Efficacy and Safety of Ridinilazole (200 mg, Bid) for 10 Days With Vancomycin (125 mg, Qid) for 10 Days in the Treatment of Clostridium Difficile Infection (CDI)

NCT03595553·Phase 3·SMMT
Completed

Primary endpoint: Number of Participants With Sustained Clinical Response (SCR) Defined as Clinical Response and no Recurrence of CDI Through 30 Days Post End of Treatment (EOT).

InterventionalRandomizedquadruple759 enrolledStarted 2019-01Completion 2021-1150 sites · Argentina, United StatesSummit Therapeutics

A Phase II, Randomized, Open-Label, Active-Controlled Clinical Study to Investigate the Safety and Efficacy of SMT19969 (200mg BID) for 10 Days Compared With Fidaxomicin (200 mg BID) for 10 Days for the Treatment of Clostridium Difficile Infection (CDI)

NCT02784002·Phase 2·SMMT
Completed

Primary endpoint: Number of treatment emergent adverse events (AEs) and serious adverse events (SAEs) to evaluate safety and tolerability

InterventionalRandomizedopen27 enrolledStarted 2014-12Completion 2016-0816 sites · Czechia, United Kingdom, United StatesSummit Therapeutics

A Phase II, Randomized, Double-Blind, Active-Controlled Clinical Study to Investigate the Efficacy and Safety of SMT19969 Compared With Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhoea (CDAD)

NCT02092935·Phase 2·SMMT
Completed

Primary endpoint: Evaluate the clinical outcome by assessment of sustained clinical response

InterventionalRandomizedquadruple100 enrolledStarted 2014-04Completion 2015-1026 sites · Canada, United StatesSummit Therapeutics