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rezpegaldesleukin

rezpegaldesleukin: developed by 1 company · 4 clinical trials tracked.

rezpegaldesleukin evidence translation

What we can confirm

What it means

Source-backed records connect rezpegaldesleukin to NKTR; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could rezpegaldesleukin → NKTR affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence2 indications · 0 study sponsors

Related indications

Moderate to Severe Atopic Dermatitis; Moderate-to-Severe Atopic Dermatitis; Alopecia AreataAlopecia Areata

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
NEKTAR THERAPEUTICS (NKTR)
Moderate to Severe Atopic Dermatitis; Moderate-to-Severe Ato…
Phase 2
Clinical Trials (4)

A Phase 3, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Rezpegaldesleukin (NKTR-358) Monotherapy in the Treatment of Patients ≥ 12 Years of Age With Moderate-to- Severe Atopic Dermatitis

NCT07711418·Phase 3·NKTR
Recruiting

Primary endpoint: US only: Number of participants with an Investigator's Global Assessment (IGA) score of 0 or 1 and reduction ≥ 2 points from baseline at Week 24

InterventionalRandomizedquadruple510 targetStarted 2026-08Completion 2029-011 site · United StatesNektar Therapeutics

A Phase 3, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Rezpegaldesleukin (NKTR-358) Monotherapy in the Treatment of Patients ≥ 12 Years of Age With Moderate-to-Severe Atopic Dermatitis

NCT07690371·Phase 3·NKTR
Recruiting

Primary endpoint: US only: Number of participants with an Investigator's Global Assessment (IGA) score of 0 or 1 and reduction ≥ 2 points from baseline at Week 24

InterventionalRandomizedquadruple510 targetStarted 2026-06Completion 2028-1212 sites · United StatesNektar Therapeutics

A Phase 2b, Randomized, Double-Blind, Parallel Group, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Rezpegaldesleukin in the Treatment of Severe to Very Severe Alopecia Areata in Adult Patients (Rezolve AA)

NCT06340360·Phase 2·NKTR
Active, not recruiting

Primary endpoint: Percent change from baseline in Severity of Alopecia Tool (SALT) score at Week 36

InterventionalRandomizedquadruple94 enrolledStarted 2024-04Completion 2026-0826 sites · Canada, Poland, United StatesNektar Therapeutics

A Phase 2b, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Rezpegaldesleukin in the Treatment of Adult Patients With Moderate-to-Severe Atopic Dermatitis (REZOLVE-AD)

NCT06136741·Phase 2·NKTR
Active, not recruiting

Primary endpoint: Mean percent change in the Eczema Area and Severity Index (EASI) from baseline at Week 16

InterventionalRandomizedquadruple396 targetStarted 2023-11Completion 2026-1250 sites · Australia, Bulgaria, Canada, United StatesNektar Therapeutics

Frequently asked questions

Who is developing rezpegaldesleukin?

rezpegaldesleukin is being developed by NEKTAR THERAPEUTICS.

How many clinical trials involve rezpegaldesleukin?

BioSniper tracks 4 clinical trials involving rezpegaldesleukin.