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ralinepag

ralinepag: developed by 2 companies · 3 clinical trials tracked.

ralinepag evidence translation

What we can confirm

3 tracked trials

What it means

More than one developer is source-backed. Until you choose one, AI stays drug-only and does not guess ownership.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about ralinepag, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence8 indications · 0 study sponsors

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (2)
CompanyPhase
ARENA PHARMACEUTICALS INC (ARNA)Phase 3
UNITED THERAPEUTICS Corp (UTHR)
PAH; Pulmonary Hypertension
Phase 3
Clinical Trials (3)

A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Ralinepag to Evaluate Safety and Effects on Exercise Capacity Assessed by CPET in Subjects With WHO Group 1 Pulmonary Hypertension Who Recently Initiated Therapy

NCT04084678·Phase 3·UTHR
Terminated

Primary endpoint: Change From Baseline in Peak VO2 Assessed by CPET

InterventionalRandomizedquadruple10 targetStarted 2021-01Completion 2023-0433 sites · Argentina, Australia, Austria, Belgium…United Therapeutics

A Phase 3 Open-label Extension (OLE) Study to Evaluate the Long-term Safety and Efficacy of Ralinepag in Subjects With World Health Organization (WHO) Group 1 Pulmonary Arterial Hypertension (PAH)

NCT03683186·Phase 3·UTHR
Enrolling by invitation

Primary endpoint: Number of subjects with treatment-emergent adverse events [Safety and Tolerability]

Interventionalopen1,000 targetStarted 2019-09Completion 2026-1250 sites · Argentina, United StatesUnited Therapeutics

A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Ralinepag When Added to PAH Standard of Care or PAH Specific Background Therapy in Subjects With WHO Group 1 PAH

NCT03626688·Phase 3·UTHR
Completed

Primary endpoint: Time from randomization to the first adjudicated protocol-defined clinical worsening event

InterventionalRandomizedquadruple687 enrolledStarted 2019-01Completion 2025-1250 sites · United StatesUnited Therapeutics

Frequently asked questions

Who is developing ralinepag?

ralinepag is being developed by ARENA PHARMACEUTICALS INC, UNITED THERAPEUTICS Corp.

How many clinical trials involve ralinepag?

BioSniper tracks 3 clinical trials involving ralinepag.