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rabeprazole

Generic: RABEPRAZOLE SODIUM·Brand: ACIPHEX, ACIPHEX SPRINKLE, Aciphex, RABEPRAZOLE SODIUM

rabeprazole: developed by 3 companies · 5 clinical trials tracked · 3 FDA decisions.

rabeprazole evidence translation

What we can confirm

3 FDA records · 5 tracked trials

What it means

More than one developer is source-backed. Until you choose one, AI stays drug-only and does not guess ownership.

What to watch

Watch active trials and any change in FDA or trial status.
BioSniper AIPage evidence connected

Prepared research question

What is verified about rabeprazole, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence2 indications · 5 study sponsors
Development Pipeline (3)
CompanyPhase
AYTU BIOPHARMA, INC (AYTU)Approved
LANNETT CO INC (LCI)Approved
DR REDDYS LABORATORIES LTD (RDY)Approved
Clinical Trials (5)

An Open-Label, Randomized, Four-Period, Six-Sequence Phase I Study to Evaluate the Effect of Food and Proton Pump Inhibitor Rabeprazole on the Pharmacokinetics of HMPL-760 Capsules in Healthy Participants

NCT07643272·Phase 1·HCM
Active, not recruiting

Primary endpoint: AUC 0-last

InterventionalRandomizedopen24 enrolledStarted 2026-06Completion 2026-121 site · ChinaHutchmed

A PHASE 1, OPEN-LABEL, RANDOMIZED, 5-PERIOD, 6-SEQUENCE, CROSSOVER STUDY TO COMPARE THE SINGLE-DOSE PHARMACOKINETICS OF ONE IMMEDIATE RELEASE AND TWO MODIFIED-RELEASE FORMULATIONS OF PF-08049820 ADMINISTERED ORALLY UNDER FASTED AND FED CONDITIONS (PART A), AND A FIXED SEQUENCE STUDY TO ASSESS THE EFFECT OF RABEPRAZOLE ON THE PHARMACOKINETICS OF PF-08049820 (PART B), IN HEALTHY ADULTS

NCT07597928·Phase 1·PFE
Recruiting

Primary endpoint: Area under the concentration-time curve from time zero to the time of the last quantifiable concentration (AUClast)

InterventionalRandomizedopen24 targetStarted 2026-05Completion 2026-091 site · United StatesPfizer

A Phase 1, Open-label, Randomized, Four-way Crossover Study to Assess the Relative Bioavailability of Two Phase 3 LY4100511 (DC-853) Tablet Formulations Compared With the Phase 2 LY4100511(DC-853) Tablet Formulation, With and Without a Proton Pump Inhibitor in Healthy Participants

NCT06916143·Phase 1·LLY
Active, not recruiting

Primary endpoint: Pharmacokinetic (PK): Area Under the Concentration Curve from 0 to Infinity (AUC0-∞) of LY4100511 (DC-853)

InterventionalRandomizedopen48 targetStarted 2025-04Completion 2026-082 sites · United StatesEli Lilly and Company

A Modular Phase I, Open-label Study to Assess the Safety, Pharmacokinetics, and Drug Interaction Potential and Relative Bioavailability of Saruparib in Patients With Advanced Solid Malignancies

NCT06899061·Phase 1·AZN
Active, not recruiting

Primary endpoint: Module 1: Area under plasma concentration-time curve from zero extrapolated to infinity (AUCinf) of digoxin, furosemide, metformin and rosuvastatin when dosed alone and in combination with saruparib

InterventionalRandomizedopen41 enrolledStarted 2025-03Completion 2028-054 sites · Bulgaria, Moldova, RomaniaAstraZeneca

A Phase 1/2 Study of BMS-986408 Alone and in Combination With Nivolumab or With Nivolumab and Ipilimumab in Participants With Advanced Solid Tumors

NCT05407675·Phase 1/Phase 2·BMY
Completed

Primary endpoint: Number of Participants With Dose Limiting Toxicities (DLTs)

Interventionalopen68 enrolledStarted 2022-08Completion 2025-0718 sites · Canada, France, Spain, Switzerland…Bristol-Myers Squibb
FDA Decisions3 records
Approval1 INDICATIONS AND USAGE Rabeprazole sodium delayed-release tablets is a proton pump inhibitor (PPI) indicated in adults for: Healing of Erosive or Ulcerative Gastroesophageal Reflux Disease (GERD) ( 1.1 ). Maintenance of Healing of Erosive or Ulcerative GERD ( 1.2 ). Treatment of Symptomatic GERD ( 1.3 ). Healing of Duodenal Ulcers ( 1.4 ). Helicobacter pylori Eradication to Reduce Risk of Duodenal Ulcer Recurrence ( 1.5 ). Treatment of Pathological Hypersecretory Conditions, Including Zollinger(RDY)FDA ↗
ANDA076824OralTablet, Delayed Release
Approval(LCI)FDA ↗
ANDA090678OralTablet, Delayed Release
Approval1 INDICATIONS AND USAGE ACIPHEX delayed-release tablets is a proton pump inhibitor (PPI) indicated in adults for: Healing of Erosive or Ulcerative Gastroesophageal Reflux Disease (GERD) ( 1.1 ). Maintenance of Healing of Erosive or Ulcerative GERD ( 1.2 ). Treatment of Symptomatic GERD ( 1.3 ). Healing of Duodenal Ulcers ( 1.4 ). Helicobacter pylori Eradication to Reduce Risk of Duodenal Ulcer Recurrence ( 1.5 ). Treatment of Pathological Hypersecretory Conditions, Including Zollinger-Ellison Sy(AYTU)FDA ↗
NDA204736Type 3 - New Dosage FormPriorityOralCapsule, Delayed Release

Frequently asked questions

Who is developing rabeprazole?

rabeprazole is being developed by AYTU BIOPHARMA, INC, LANNETT CO INC, DR REDDYS LABORATORIES LTD.

How many clinical trials involve rabeprazole?

BioSniper tracks 5 clinical trials involving rabeprazole.

What is rabeprazole's latest FDA decision?

The most recent tracked FDA decision for rabeprazole is Approval for 1 INDICATIONS AND USAGE Rabeprazole sodium delayed-release tablets is a proton pump inhibitor (PPI) indicated in adults for: Healing of Erosive or Ulcerative Gastroesophageal Reflux Disease (GERD) ( 1.1 ). Maintenance of Healing of Erosive or Ulcerative GERD ( 1.2 ). Treatment of Symptomatic GERD ( 1.3 ). Healing of Duodenal Ulcers ( 1.4 ). Helicobacter pylori Eradication to Reduce Risk of Duodenal Ulcer Recurrence ( 1.5 ). Treatment of Pathological Hypersecretory Conditions, Including Zollinger, dated November 8, 2013.