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psilocybin

psilocybin: 17 clinical trials tracked.

psilocybin evidence translation

What we can confirm

17 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about psilocybin, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence5 indications · 5 study sponsors
Clinical Trials (17)showing 10 most recent

Inpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder: a Randomized Double-blind Trial

NCT06005662·Phase 2·COLL
Withdrawn

Primary endpoint: Opioid Abstinence

InterventionalRandomizedquadruple0 targetStarted 2027-04Completion 2028-071 site · United StatesJohns Hopkins University

Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies

NCT07745569·Phase 2
Not yet recruiting

Primary endpoint: Neurofeedback

Interventionalopen150 targetStarted 2026-08Completion 2030-06University of New Mexico

Safety, Tolerability, Outcomes of Psilocybin for Depression (STOP Depression) in Veterans With Spinal Cord Injury

NCT07251491·Phase 1/Phase 2
Recruiting

Primary endpoint: Number of Participants with Treatment-Related Adverse Events as Assessed by the Adverse Events Log.

Interventionaltriple30 targetStarted 2026-08Completion 2028-031 site · United StatesJames J. Peters Veterans Affairs Medical Center

A Multi-site Randomized Controlled Trial of Psilocybin for Treatment-Resistant Depression (TRD) in Veterans

NCT07226232·Phase 3·GHRS
Recruiting

Primary endpoint: Montgomery-Asberg Rating Scale (MADRS)

InterventionalRandomizedquadruple240 targetStarted 2026-08Completion 2031-065 sites · United StatesVA Office of Research and Development

Targeting Reward Circuits: Psilocybin as a Novel Therapy for Residual Anhedonia

NCT07607938·Phase 1
Not yet recruiting

Primary endpoint: Change in Dimensional Anhedonia Rating Scale (DARS) Score

InterventionalRandomizedtriple90 targetStarted 2026-07Completion 2030-091 site · United StatesNYU Langone Health

A Phase 2, Open-Label Study Investigating the Safety and Efficacy of Psilocybin-Assisted Therapy for Sexual Assault-Related Posttraumatic Stress Disorder (PTSD)

NCT06902974·Phase 2·WOK
Recruiting

Primary endpoint: To assess the safety and tolerability of psilocybin-assisted therapy in adult participants with PTSD secondary to sexual assault

Interventionalopen70 targetStarted 2026-05Completion 2028-051 site · United StatesSunstone Medical

PSilocybin Microdose for psYCHological and Existential Distress in PALliative Care (PSYCHED-PAL): A Multi-site Phase 3 Double-blind, Placebo-controlled, Parallel-arm Clinical Trial

NCT07063862·Phase 3·GHRS
Recruiting

Primary endpoint: Change in Psychological Distress - Patient Global Impression of Change

InterventionalRandomizedquadruple120 targetStarted 2026-01Completion 2027-097 sites · CanadaBruyère Health Research Institute.

Effects of Psilocybin in Patients With Amyotrophic Lateral Sclerosis

NCT06656702·Early Phase 1
Recruiting

Primary endpoint: Feasibility of psilocybin treatment as assessed by number of participants recruited, retained and adhere to treatment

Interventionalopen24 targetStarted 2025-04Completion 2027-071 site · United StatesJohns Hopkins University

Pragmatic Trial of Psilocybin Therapy in Palliative Care (PT2PC): A Multicenter Triple-blind Phase 2 Randomized Controlled Trial of Psilocybin Therapy for Demoralized Adults Near the End of Life

NCT05403086·Phase 2
Recruiting

Primary endpoint: Change in patient-reported Demoralization Scale-II..

InterventionalRandomizedquadruple100 targetStarted 2025-01Completion 2027-125 sites · United StatesCharles S. Grob, M.D.

The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive Disorder

NCT06247839·Phase 3
Recruiting

Primary endpoint: Change in Massachusetts General Hospital Rumination Questionnaire (MGH-RQ)

Interventionalopen20 targetStarted 2024-09Completion 2028-061 site · United StatesSharmin Ghaznavi