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prt3789

·Code: PRT3789

prt3789: developed by 1 company · 2 clinical trials tracked.

prt3789 evidence translation

What we can confirm

What it means

Source-backed records connect prt3789 to PRLD; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could prt3789 → PRLD affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence2 indications · 0 study sponsors

Related indications

Advanced Solid TumorEsophageal Cancer

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
Prelude Therapeutics Inc (PRLD)
Advanced Solid Tumor
Phase 2
Clinical Trials (2)

A Phase 2, Safety and Efficacy Study of PRT3789 in Combination With Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

NCT06682806·Phase 2·PRLD
Terminated

Primary endpoint: Safety and tolerability of PRT3789 in combination with pembrolizumab as measured by incidence of DLTs (Part 1)

Interventionalopen6 targetStarted 2025-06Completion 2026-019 sites · Spain, United StatesPrelude Therapeutics

A Phase 1 Open-Label, Multi-Center, Safety and Efficacy Study of PRT3789 as Monotherapy and in Combination With Docetaxel in Participants With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

NCT05639751·Phase 1·PRLD
Completed

Primary endpoint: Dose limiting toxicity (DLT) of PRT3789 monotherapy and in combination with docetaxel

Interventionalopen135 enrolledStarted 2023-05Completion 2025-1032 sites · France, Netherlands, Singapore, Spain…Prelude Therapeutics

Frequently asked questions

Who is developing prt3789?

prt3789 is being developed by Prelude Therapeutics Inc.

How many clinical trials involve prt3789?

BioSniper tracks 2 clinical trials involving prt3789.