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poziotinib

poziotinib: sourced relationships with 2 companies · 3 clinical trials tracked.

poziotinib evidence translation

What we can confirm

3 tracked trials

What it means

More than one company relationship is source-backed. Until you choose one, AI stays drug-only and does not guess ownership.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about poziotinib, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence2 indications · 0 study sponsors

Related indications

Under investigation for non-small cell lung cancer tumors with various mutations.NSCLC

Study sponsors

No additional listed-company sponsor is linked.

Dated Pipeline Records (2)
CompanyDated record stage
Assertio Holdings, Inc. (ASRT)
licensee · Reported 2024-03-11 · Current development: unknownSource
Under investigation for non-small cell lung cancer tumors wi…
Phase 2
SPECTRUM PHARMACEUTICALS INC (SPPI)
co_developer · Reported 2022-03-18 · Current development: unknownSource
Phase 3
Clinical Trial Registry Records (3)

A Randomized, Phase 3 Study of Poziotinib in Previously Treated Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) Harboring HER2 Exon 20 Mutations (PINNACLE)

NCT05378763Registry updated 2026-05-22·Phase 3·SPPI
Suspended

Primary endpoint: Progression Free Survival (PFS)

InterventionalRandomizedopen268 targetStarted 2022-05Completion 2028-121 site · United StatesSpectrum Pharmaceuticals, Inc

A Phase 2 Study of Poziotinib in Patients With Non-Small Cell Lung Cancer (NSCLC), Locally Advanced or Metastatic, With EGFR or HER2 Exon 20 Insertion Mutation (ZENITH20)

NCT03318939Registry updated 2026-06-12·Phase 2·SPPI
Terminated

Primary endpoint: Objective Response Rate (ORR)

InterventionalRandomizedopen648 targetStarted 2017-10Completion 2023-0450 sites · Belgium, Canada, United StatesSpectrum Pharmaceuticals, Inc

A Phase II Study of Poziotinib in EGFR or HER2 Mutant Advanced Solid Tumors

NCT03066206Registry updated 2026-02-20·Phase 2
Terminated

Primary endpoint: Objective response rate a in patients with estimated glomerular filtration rate (EGFR) exon 20 mutant non-small Cell Lung Cancer (NSCLC) (Cohort 1)

Interventionalopen93 targetStarted 2017-03Completion 2026-021 site · United StatesM.D. Anderson Cancer Center

Frequently asked questions

Which companies have sourced relationships with poziotinib?

poziotinib has dated SEC/FDA relationship records for Assertio Holdings, Inc., SPECTRUM PHARMACEUTICALS INC.

How many clinical trials involve poziotinib?

BioSniper tracks 3 clinical trials involving poziotinib.