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pelareorep

pelareorep: developed by 1 company · 3 clinical trials tracked.

pelareorep evidence translation

What we can confirm

What it means

Source-backed records connect pelareorep to ONCY; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could pelareorep → ONCY affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence1 indications · 0 study sponsors

Related indications

Ras-mutated Metastatic Colorectal Cancer; Anal Cancer Metastatic

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
ONCOLYTICS BIOTECH INC (ONCY)
Ras-mutated Metastatic Colorectal Cancer; Anal Cancer Metast…
Phase 1/Phase 2
Clinical Trials (3)

An Open-Label, Randomized, Multicentre, Phase 2 Study of FOLFIRI + Bevacizumab + Pelareorep vs. FOLFIRI + Bevacizumab for the Second-Line Treatment of Metastatic, RAS-mutated, Microsatellite-Stable (MSS) Colorectal Cancer

NCT07446322·Phase 2·ONCY
Recruiting

Primary endpoint: Overall Response Rate (ORR)

InterventionalRandomizedopen60 targetStarted 2026-04Completion 2030-0413 sites · United StatesOncolytics Biotech

A Phase 1 / 2 Multiple-indication Biomarker, Safety, and Efficacy Study in Advanced or Metastatic Gastrointestinal Cancers Exploring Treatment Combinations With Pelareorep and Atezolizumab

NCT07280377·Phase 1/Phase 2·ONCY
Active, not recruiting

Primary endpoint: Overall Response Rate (ORR) for Cohort 1, 2, 4, and 5

Interventionalopen122 targetStarted 2021-10Completion 2028-1215 sites · GermanyOncolytics Biotech

IRENE Study: Phase 2 Study of INCMGA00012 and the Oncolytic Virus Pelareorep in Metastatic Triple Negative Breast Cancer

NCT04445844·Phase 2

Primary endpoint: Objective response rate (ORR)

Interventionalopen25 targetStarted 2020-07Completion 2025-062 sites · United StatesMridula George, MD

Frequently asked questions

Who is developing pelareorep?

pelareorep is being developed by ONCOLYTICS BIOTECH INC.

How many clinical trials involve pelareorep?

BioSniper tracks 3 clinical trials involving pelareorep.