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pd-l1 inhibitor incb099280

Generic: PD-L1 Inhibitor INCB099280

pd-l1 inhibitor incb099280: 7 clinical trials tracked.

pd-l1 inhibitor incb099280 evidence translation

What we can confirm

7 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about pd-l1 inhibitor incb099280, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence8 indications · 1 study sponsors
Clinical Trials (7)

An Open-Label Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]INCB099280 in Healthy Male Participants

NCT06309394·Phase 1·INCY
Completed

Primary endpoint: Total Recovery (Urine + Feces) of the Administered Radioactivity

Interventionalopen5 enrolledStarted 2024-05Completion 2024-061 site · United KingdomIncyte Corporation

A Pilot Study of Neoadjuvant INCB099280 in Patients With Hepatocellular Carcinoma Awaiting Liver Transplant

NCT06337162·Phase 1
Withdrawn

Primary endpoint: Acute Cellular Rejection of Liver Transplant Attributed to Study Therapy

Interventionalopen0 targetStarted 2024-05Completion 2028-091 site · United StatesAbramson Cancer Center at Penn Medicine

A Phase 1/2 Study of INCB099280 in Combination With Axitinib in Adults With Advanced Solid Tumors

NCT05949632·Phase 1/Phase 2·INCY
Terminated

Primary endpoint: Part 1: Number of Participants With Dose-limiting Toxicities (DLTs)

Interventionalopen5 targetStarted 2024-04Completion 2025-066 sites · United KingdomIncyte Corporation

A Phase 1 Study of INCB099280 in Combination With Adagrasib in Adults With Advanced Solid Tumors Harboring a KRASG12C Mutation

NCT06039384·Phase 1·INCY
Terminated

Primary endpoint: Part 1: Number of participants with Dose Limiting Toxicities (DLTs)

InterventionalRandomizedopen6 targetStarted 2023-12Completion 2025-0714 sites · Italy, Spain, United Kingdom, United StatesIncyte Corporation

A Phase 2 Study Evaluating INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor Naive

NCT05879822·Phase 2·INCY

Primary endpoint: Objective response rate (ORR)

InterventionalRandomizedopen73 targetStarted 2023-10Completion 2026-0750 sites · Brazil, China, Georgia, Greece…Incyte Corporation

A Phase 2 Study Evaluating INCB099280 in Participants With Advanced Squamous Cell Carcinoma

NCT05888844·Phase 2·INCY
Active, not recruiting

Primary endpoint: Objective response rate (ORR)

InterventionalRandomizedopen63 enrolledStarted 2023-10Completion 2026-0950 sites · Australia, Brazil, Canada, Chile…Incyte Corporation

A Phase 1 Study Exploring the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Select Advanced Solid Tumors

NCT04242199·Phase 1·INCY
Completed

Primary endpoint: Number of treatment-emergent adverse events

Interventionalopen182 enrolledStarted 2020-09Completion 2024-1121 sites · Australia, Belgium, France, Japan…Incyte Corporation