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pd-l1 inhibitor incb099280

Generic: PD-L1 Inhibitor INCB099280

pd-l1 inhibitor incb099280: 7 clinical trials tracked.

pd-l1 inhibitor incb099280 evidence translation

What we can confirm

7 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about pd-l1 inhibitor incb099280, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence8 indications · 1 study sponsors
Clinical Trial Registry Records (7)

An Open-Label Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]INCB099280 in Healthy Male Participants

NCT06309394Registry updated 2025-09-11·Phase 1·INCY
Completed

Primary endpoint: Total Recovery (Urine + Feces) of the Administered Radioactivity

Interventionalopen5 enrolledStarted 2024-05Completion 2024-061 site · United KingdomIncyte Corporation

A Pilot Study of Neoadjuvant INCB099280 in Patients With Hepatocellular Carcinoma Awaiting Liver Transplant

NCT06337162Registry updated 2024-08-09·Phase 1
Withdrawn

Primary endpoint: Acute Cellular Rejection of Liver Transplant Attributed to Study Therapy

Interventionalopen0 targetStarted 2024-05Completion 2028-091 site · United StatesAbramson Cancer Center at Penn Medicine

A Phase 1/2 Study of INCB099280 in Combination With Axitinib in Adults With Advanced Solid Tumors

NCT05949632Registry updated 2026-06-04·Phase 1/Phase 2·INCY
Terminated

Primary endpoint: Part 1: Number of Participants With Dose-limiting Toxicities (DLTs)

Interventionalopen5 targetStarted 2024-04Completion 2025-066 sites · United KingdomIncyte Corporation

A Phase 1 Study of INCB099280 in Combination With Adagrasib in Adults With Advanced Solid Tumors Harboring a KRASG12C Mutation

NCT06039384Registry updated 2026-09-08·Phase 1·INCY
Terminated

Primary endpoint: Number of Participants With Dose-limiting Toxicities (DLTs)

InterventionalRandomizedopen6 enrolledStarted 2023-12Completion 2025-0714 sites · Italy, Spain, United Kingdom, United StatesIncyte Corporation

A Phase 2 Study Evaluating INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor Naive

NCT05879822Registry updated 2026-09-02·Phase 2·INCY
Active, not recruiting

Primary endpoint: Objective response rate (ORR)

InterventionalRandomizedopen73 enrolledStarted 2023-10Completion 2026-0950 sites · Brazil, China, Georgia, Greece…Incyte Corporation

A Phase 2 Study Evaluating INCB099280 in Participants With Advanced Squamous Cell Carcinoma

NCT05888844Registry updated 2026-08-17·Phase 2·INCY
Active, not recruiting

Primary endpoint: Objective response rate (ORR)

InterventionalRandomizedopen63 enrolledStarted 2023-10Completion 2026-0950 sites · Australia, Brazil, Canada, Chile…Incyte Corporation

A Phase 1 Study Exploring the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Select Advanced Solid Tumors

NCT04242199Registry updated 2025-07-14·Phase 1·INCY
Completed

Primary endpoint: Number of treatment-emergent adverse events

Interventionalopen182 enrolledStarted 2020-09Completion 2024-1121 sites · Australia, Belgium, France, Japan…Incyte Corporation