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obexelimab

obexelimab: developed by 2 companies · 4 clinical trials tracked.

obexelimab evidence translation

What we can confirm

4 tracked trials

What it means

More than one developer is source-backed. Until you choose one, AI stays drug-only and does not guess ownership.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about obexelimab, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence4 indications · 0 study sponsors

Related indications

immunoglobulin G4-related disease (IgG4-RD); warm autoimmune hemolytic anemia (wAIHA)Warm Autoimmune Hemolytic Anemia; IgG4 Related Disease; Relapsing Multiple SclerosisRelapsing Multiple SclerosisSystemic Lupus Erythematosus

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (2)
CompanyPhase
Xencor Inc (XNCR)
immunoglobulin G4-related disease (IgG4-RD); warm autoimmune…
Phase 3
Zenas BioPharma, Inc. (ZBIO)
Warm Autoimmune Hemolytic Anemia; IgG4 Related Disease; Rela…
Phase 3
Clinical Trials (4)

A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Obexelimab in Patients With Systemic Lupus Erythematosus

NCT06559163·Phase 2·ZBIO
Active, not recruiting

Primary endpoint: Primary Outcome Measure

InterventionalRandomizedquadruple190 enrolledStarted 2024-09Completion 2026-1250 sites · Belgium, Bulgaria, Canada, China…Zenas BioPharma (USA), LLC

A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Obexelimab in Patients With Relapsing Multiple Sclerosis

NCT06564311·Phase 2·ZBIO

Primary endpoint: Cumulative number of new GdE T1 hyperintense lesions

InterventionalRandomizedquadruple93 targetStarted 2024-08Completion 2026-0247 sites · Austria, Belgium, China, Croatia…Zenas BioPharma (USA), LLC

A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study With An Open Label Safety and Dose Confirmation Run-In Period, To Evaluate the Efficacy and Safety of Obexelimab in Patients With Warm Autoimmune Hemolytic Anemia (SApHiAre)

NCT05786573·Phase 3·ZBIO

Primary endpoint: Safety and Dose Confirmation Run-in Period (SRP)

InterventionalRandomizedquadruple134 targetStarted 2023-09Completion 2026-087 sites · Italy, Poland, Spain, Taiwan…Zenas BioPharma (USA), LLC

A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Obexelimab in Patients With IgG4-Related Disease (INDIGO)

NCT05662241·Phase 3·ZBIO

Primary endpoint: Primary outcome measure

InterventionalRandomizedquadruple194 targetStarted 2023-01Completion 2029-0250 sites · Argentina, Canada, China, France…Zenas BioPharma (USA), LLC

Frequently asked questions

Who is developing obexelimab?

obexelimab is being developed by Xencor Inc, Zenas BioPharma, Inc..

How many clinical trials involve obexelimab?

BioSniper tracks 4 clinical trials involving obexelimab.