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numidargistat

Generic: Numidargistat

numidargistat: developed by 1 company · 3 clinical trials tracked.

numidargistat evidence translation

What we can confirm

What it means

Source-backed records connect numidargistat to CALA; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could numidargistat → CALA affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence8 indications · 1 study sponsors
Development Pipeline (1)
CompanyPhase
Calithera Biosciences, Inc. (CALA)
Oncology and hematology indications
Phase 1
Clinical Trials (3)

A Randomized Open-Label Phase 1/2 Study of INCB001158 Combined With Subcutaneous (SC) Daratumumab, Compared to Daratumumab SC, in Participants With Relapsed or Refractory Multiple Myeloma

NCT03837509·Phase 1/Phase 2·INCY
Terminated

Primary endpoint: Phase 1: Number of Participants With Any Treatment-emergent Adverse Event (TEAE)

InterventionalRandomizedopen15 targetStarted 2019-09Completion 2022-0429 sites · Germany, Spain, United StatesIncyte Corporation

A Phase 1/2 Study to Evaluate the Safety, Tolerability, and Efficacy of INCB001158 in Combination With Chemotherapy, in Subjects With Advanced or Metastatic Solid Tumors

NCT03314935·Phase 1/Phase 2·INCY
Completed

Primary endpoint: Phases 1 and 2: Number of Participants With Any Treatment-emergent Adverse Event (TEAE)

Interventionalopen149 enrolledStarted 2017-11Completion 2022-1110 sites · Belgium, United Kingdom, United StatesIncyte Corporation

Safety, Pharmacokinetics, and Pharmacodynamics of Escalating Oral Doses of the Arginase Inhibitor INCB001158 (Formerly Known as CB1158) as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors

NCT02903914·Phase 1·INCY
Completed

Primary endpoint: Number of Participants With Any Treatment-emergent Adverse Event (TEAE)

Interventionalopen260 enrolledStarted 2016-09Completion 2022-0820 sites · Italy, Netherlands, Spain, United StatesIncyte Corporation

Frequently asked questions

Who is developing numidargistat?

numidargistat is being developed by Calithera Biosciences, Inc..

How many clinical trials involve numidargistat?

BioSniper tracks 3 clinical trials involving numidargistat.