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neflamapimod

neflamapimod: developed by 1 company · 4 clinical trials tracked.

neflamapimod evidence translation

What we can confirm

4 tracked trials

What it means

Source-backed records connect neflamapimod to CRVO; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could neflamapimod → CRVO affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence1 indications · 0 study sponsors

Related indications

dementia with Lewy bodies (DLB)

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
CervoMed Inc. (CRVO)
dementia with Lewy bodies (DLB)
Phase 2
Clinical Trials (4)

A Phase 2a Clinical Study of the P38 Alpha Kinase Inhibitor Neflamapimod in Patients With Primary Progressive Aphasia (PPA)

NCT07033481·Phase 2
Active, not recruiting

Primary endpoint: Incidence of Adverse Events and Serious Adverse Events.

InterventionalRandomizedquadruple20 targetStarted 2025-10Completion 2026-107 sites · United Kingdom, United StatesEIP Pharma Inc

A Double-Blind, Placebo-Controlled, Proof-of-Concept Clinical Study of the P38 Alpha Kinase Inhibitor Neflamapimod on Recovery After Moderate to Severe Acute Ischaemic Stroke

NCT06987643·Phase 2
Active, not recruiting

Primary endpoint: Change from baseline to Week 12 in Fugl-Meyer Assessment of Motor Recovery after Stroke (FMMS) motor score (upper and lower) and total score

InterventionalRandomizedquadruple90 targetStarted 2025-06Completion 2026-1010 sites · AustraliaEIP Pharma Inc

An Open-Label Phase 2a Clinical Study of the P38 Alpha Kinase Inhibitor Neflamapimod in Patients With Dementia With Lewy Bodies (DLB)

NCT06815965·Phase 2
Completed

Primary endpoint: Evaluate the safety and tolerability 80 mg neflamapimod given twice daily in patients with dementia with Lewy bodies.

Interventionalopen26 enrolledStarted 2024-10Completion 2026-032 sites · FranceEIP Pharma Inc

A Phase 2b Clinical Study of the P38 Alpha Kinase Inhibitor Neflamapimod in Patients With Dementia With Lewy Bodies

NCT05869669·Phase 2
Completed

Primary endpoint: Change in Clinical Dementia Rating Scale - Sum of Boxes (CDR-SB) in neflamapimod-treated subjects compared to placebo recipients.

InterventionalRandomizedquadruple159 enrolledStarted 2023-05Completion 2025-0640 sites · Netherlands, United Kingdom, United StatesEIP Pharma Inc

Frequently asked questions

Who is developing neflamapimod?

neflamapimod is being developed by CervoMed Inc..

How many clinical trials involve neflamapimod?

BioSniper tracks 4 clinical trials involving neflamapimod.