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momelotinib

Generic: MOMELOTINIB DIHYDROCHLORIDE·Brand: OJJAARA, Ojjaara

momelotinib: developed by 1 company · 4 clinical trials tracked.

momelotinib evidence translation

What we can confirm

What it means

Source-backed records connect momelotinib to SRRA; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could momelotinib → SRRA affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence4 indications · 2 study sponsors
Development Pipeline (1)
Clinical Trials (4)

Phase Ib/II Study Of Revumenib As Monotherapy Or In Combination With Jak Inhibitors In Patients With Myelofibrosis

NCT07734077·Phase 1/Phase 2
Not yet recruiting

Primary endpoint: Dose limiting toxicity (DLT)

Interventionalopen32 targetStarted 2026-12Completion 2028-121 site · United StatesJohn Mascarenhas

A Pilot Study of Momelotinib in Combination With Hypomethylating Agent for Chronic Phase Myelodysplastic Syndromes/Myeloproliferative Overlap Neoplasms and Chronic Neutrophilic Leukemia (M-HArbOr)

NCT07071155·Early Phase 1
Recruiting

Primary endpoint: Number of participants who achieve a complete response

Interventionalopen18 targetStarted 2026-03Completion 2028-071 site · United StatesSidney Kimmel Comprehensive Cancer Center at Johns Hopkins

A Phase 2 Study to Evaluate the Efficacy and Safety of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia

NCT05980806·Phase 2·KPTI
Recruiting

Primary endpoint: Proportion of Participants with Spleen Volume Reduction ≥35% (SVR35) at Week 24

Interventionalopen58 targetStarted 2024-04Completion 2028-1050 sites · Belgium, Bulgaria, Canada, Czechia…Karyopharm Therapeutics Inc

A First-in-Human Study of the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-88549968, a T-cell Redirecting Bispecific Antibody for CALR-mutated Myeloproliferative Neoplasms

NCT06150157·Phase 1·GHRS
Recruiting

Primary endpoint: Part 1, Part 1b (US Only): Number of Participants With Dose Limiting Toxicity (DLT)

Interventionalopen241 targetStarted 2023-12Completion 2028-0639 sites · Canada, China, France, Germany…Janssen Research & Development, LLC

Frequently asked questions

Who is developing momelotinib?

momelotinib is being developed by Sierra Oncology, Inc..

How many clinical trials involve momelotinib?

BioSniper tracks 4 clinical trials involving momelotinib.