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mn-166

Generic: ibudilast·Code: MN-166

mn-166: developed by 1 company · 3 clinical trials tracked.

mn-166 evidence translation

What we can confirm

3 tracked trials

What it means

Source-backed records connect mn-166 to MNOV; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could mn-166 → MNOV affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence4 indications · 0 study sponsors

Related indications

Amyotrophic Lateral Sclerosis; GlioblastomaAmyotrophic Lateral SclerosisGlioblastomaRecurrent Glioblastoma

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
MEDICINOVA INC (MNOV)
Amyotrophic Lateral Sclerosis; Glioblastoma
Phase 1/Phase 2
Clinical Trials (3)

Scalable Expanded Access With Analysis of Neurofilament and Other Biomarkers for Ibudilast in ALS

No longer available
Expanded Access15 sites · United StatesMayo Clinic

A Phase 2b/3, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, 12 Month Clinical Trial to Evaluate the Efficacy and Safety of MN-166 (Ibudilast) Followed by Open-Label Extension Phase in Subjects With Amyotrophic Lateral Sclerosis

NCT04057898·Phase 2/Phase 3·MNOV

Primary endpoint: Change from baseline in ALSFRS-R score at Month 12 (or last measurement before death in case of censoring) and survival time.

InterventionalRandomizedquadruple234 targetStarted 2020-05Completion 2028-0416 sites · Canada, United StatesMediciNova

Phase 1b/2a Single-center, Open-label, Dose Escalation Study to Evaluate the Safety, Tolerability, and Efficacy of MN-166 (Ibudilast) and Temozolomide Combination Treatment in Patients With Newly Diagnosed or Recurrent Glioblastoma

NCT03782415·Phase 1/Phase 2·MNOV
Completed

Primary endpoint: Evaluate safety and tolerability of ibudilast and temozolomide combination treatment

Interventionalopen64 enrolledStarted 2018-12Completion 2023-081 site · United StatesMediciNova

Frequently asked questions

Who is developing mn-166?

mn-166 is being developed by MEDICINOVA INC.

How many clinical trials involve mn-166?

BioSniper tracks 3 clinical trials involving mn-166.