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methadone

Generic: METHADONE HYDROCHLORIDE·Brand: DOLOPHINE HYDROCHLORIDE, Diskets, Dolophine, METHADONE HYDROCHLORIDE, METHADONE HYDROCHLORIDE INTENSOL, METHADOSE, Methadose, WESTADONE

methadone: 4 clinical trials tracked.

methadone evidence translation

What we can confirm

4 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about methadone, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence2 indications · 0 study sponsors

Study sponsors

No additional listed-company sponsor is linked.

Clinical Trials (4)

A Clinical Trial to Study the Effect of a Single Dose of Ulonivirine on the Pharmacokinetics of Methadone

NCT07595263·Phase 1
Not yet recruiting

Primary endpoint: Dose-Normalized Area Under the Plasma Concentration Time Curve From 0-24 Hours Postdose (AUC0-24) of R-Methadone

Interventionalopen14 targetStarted 2026-08Completion 2027-011 site · United StatesMerck Sharp & Dohme LLC

A Clinical Trial to Study the Effect of a Single Dose of MK-8527 on the Pharmacokinetics of Methadone

NCT07528508·Phase 1
Completed

Primary endpoint: Dose-Normalized Area Under the Plasma Concentration Time Curve From 0-24 Hours Postdose (AUC0-24) of R-Methadone

Interventionalopen14 enrolledStarted 2026-05Completion 2026-071 site · United StatesMerck Sharp & Dohme LLC

Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment - A Pragmatic Hybrid Effectiveness/Implementation Trial

NCT06323824·Phase 4
Recruiting

Primary endpoint: Number of days of continuous treatment with study site clinician-prescribed methadone or buprenorphine, as randomized, during the 168 days post-randomization among RCT participants.

InterventionalRandomizedopen600 targetStarted 2024-06Completion 2028-126 sites · United StatesYale University

Effects of Mu-opiate Receptor Engagement on Microbial Translocation and Residual Immune Activation in HIV-infected, ART Suppressed Opioid Use Disorder Patients Initiating Medication-assisted Treatment

NCT04480554·Phase 2
Terminated

Primary endpoint: Change in sCD14

InterventionalRandomizedopen78 targetStarted 2023-01Completion 2025-062 sites · United States, VietnamUniversity of Pennsylvania