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lutetium lu 177 dotatate

Generic: LUTETIUM LU 177 DOTATATE·Brand: LUTATHERA

lutetium lu 177 dotatate: 8 clinical trials tracked.

lutetium lu 177 dotatate evidence translation

What we can confirm

8 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
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Prepared research question

What is verified about lutetium lu 177 dotatate, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence1 indications · 0 study sponsors

Related indications

Study sponsors

No additional listed-company sponsor is linked.

Clinical Trial Registry Records (8)

A Phase II Pilot Study of (Lutetium (177Lu)-DOTATATE in Patients With Metastatic Breast Cancer

NCT04529044Registry updated 2026-06-05·Phase 2
Recruiting

Primary endpoint: Objective response rate (ORR)

Interventionalopen10 targetStarted 2026-06Completion 2027-121 site · United StatesOHSU Knight Cancer Institute

NET RETREAT: A Phase II Study of 177 Lutetium-DOTATATE Retreatment vs. Everolimus or Sunitinib or Cabozantinib in Metastatic/Unresectable Gastroenteropancreatic Neuroendocrine Tumours

NCT05773274Registry updated 2026-02-20·Phase 2
Recruiting

Primary endpoint: Progression-free survival (PFS)

InterventionalRandomizedopen100 targetStarted 2024-01Completion 2026-0432 sites · Canada, United StatesNational Cancer Institute (NCI)

A Single Arm Study With Safety Run-in of Peptide Receptor Radionuclide Therapy (PRRT) in Combination With Immunotherapy for Patients With Merkel Cell Cancer (HCRN MCC20-443; iPRRT Study)

NCT05583708Registry updated 2026-04-22·Phase 2
Recruiting

Primary endpoint: Objective Response Rate (ORR)

Interventionalopen18 targetStarted 2023-08Completion 2028-123 sites · United StatesWeill Medical College of Cornell University

Phase II Randomized, Prospective Trial of Lutetium Lu 177 Dotatate PRRT Versus Capecitabine and Temozolomide in Well-Differentiated Pancreatic Neuroendocrine Tumors

NCT05247905Registry updated 2026-09-02·Phase 2
Active, not recruiting

Primary endpoint: Progression free survival (PFS)

InterventionalRandomizedopen31 enrolledStarted 2023-02Completion 2033-1050 sites · United StatesAlliance for Clinical Trials in Oncology

Randomized Phase II Trial of Lutetium Lu 177 Dotatate Versus Everolimus in Somatostatin Receptor Positive Bronchial Neuroendocrine Tumors

NCT04665739Registry updated 2026-02-20·Phase 2
Recruiting

Primary endpoint: Median progression-free survival (PFS)

InterventionalRandomizedopen70 targetStarted 2023-02Completion 2033-0129 sites · United StatesNational Cancer Institute (NCI)

A Phase 1b Trial of M3814 (Peposertib) in Combination With Lutetium 177 Dotatate for Well-Differentiated Somatostatin Receptor-Positive Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs)

NCT04750954Registry updated 2026-02-25·Phase 1
Active, not recruiting

Primary endpoint: Recommended phase 2 dose

Interventionalopen29 targetStarted 2021-07Completion 2026-065 sites · United StatesNational Cancer Institute (NCI)

Phase 1 Study of Perioperative Peptide Receptor Radionuclide Therapy (PRRT) in Metastatic, WHO Grade 1 or 2, SSTR Positive, Gastroenteropancreatic Neuroendocrine Tumors Who Are Candidates for Cytoreductive Surgery

NCT04609592Registry updated 2026-08-12·Phase 1
Active, not recruiting

Primary endpoint: Measure Complication free Surgery

Interventionalopen10 enrolledStarted 2021-03Completion 2027-051 site · United StatesStanford University

Two Steps Italian Prospective obsErvationAL Study Assessing the Effectiveness and Outcomes Associated With LUtathera (177Lu) Oxodotreotide Treatment in Adult Subjects With Unresectable or Metastatic, Progressive, Well Differentiated (G1 and G2), Somatostatin Receptor Positive Gastroenteropancreatic-neuroendocrine Tumours (GEP-NETs) - REAL-LU

NCT04727723Registry updated 2026-05-04
Completed

Primary endpoint: Progression Free Survival (PFS)

Observational164 enrolledStarted 2021-03Completion 2026-0318 sites · ItalyNovartis Pharmaceuticals