lithium
lithium: 3 clinical trials tracked.
lithium evidence translation
What we can confirm
3 tracked trials
What it means
What to watch
Prepared research question
What is verified about lithium, and what remains unknown?
Traceable citations · Unknowns marked
See linked entities and source evidence1 indications · 1 study sponsors
Related indications
Study sponsors
Clinical Trial Registry Records (3)
A Phase 3, Open-label Extension Study to Assess the Long-term Safety of KarXT for the Treatment of Mania or Mania With Mixed Features in Bipolar-I Disorder (BALSAM-3)
Primary endpoint: Number of participants with treatment emergent adverse events (TEAEs)
A Phase 1, 6-part, Open-label, Fixed-sequence Study to Evaluate the Effects of Lithium, Valproic Acid, and Lamotrigine on the Single-dose Pharmacokinetics of KarXT and Effects of KarXT on the Single-dose Pharmacokinetics of Lithium, Valproic Acid, and Lamotrigine in Healthy Participants
Primary endpoint: Maximum observed plasma concentration (Cmax)
Characterization and Pathophysiology of Severe Mood and Behavioral Dysregulation in Children and Youth
Primary endpoint: To examine between-group differences in clinical, behavioral, genetic, neuroanatomical, and neurophysiological variables