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leflunomide

Generic: LEFLUNOMIDE·Brand: ARAVA, LEFLUNOMIDE

leflunomide: 5 clinical trials tracked.

leflunomide evidence translation

What we can confirm

5 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about leflunomide, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence3 indications · 1 study sponsors
Clinical Trial Registry Records (5)

Phase I/II Study of Leflunomide in Combination With Decitabine for Treatment of Relapsed or Refractory (R/R) Myelodysplastic Syndromes (MDS)

NCT06923488Registry updated 2026-04-23·Phase 1/Phase 2
Recruiting

Primary endpoint: Percentage of incidences of regimen limiting toxicities (RLTs)

Interventionalopen26 targetStarted 2025-07Completion 2028-101 site · United StatesWest Virginia University

Post Authorization Safety Study on Assessment of Effectiveness of Additional Risk Minimization Measures Related to ARAVA® (Leflunomide) in Saudi Arabia

NCT06714461Registry updated 2026-06-11·SNY
Completed

Primary endpoint: Number of healthcare professionals who recall receiving and reading the additional risk minimization measures material for leflunomide distributed in 2022

Observational302 enrolledStarted 2025-05Completion 2026-051 site · FranceSanofi

Pilot Trial of Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies

NCT05443425Registry updated 2026-07-08·Phase 1
Recruiting

Primary endpoint: Incidence of adverse events

Interventionalopen18 targetStarted 2023-06Completion 2027-011 site · United StatesCity of Hope Medical Center

A Phase 2 Trial of Leflunomide, Pomalidomide, and Dexamethasone for Relapsed/Refractory Multiple Myeloma

NCT04508790Registry updated 2026-05-29·Phase 2
Recruiting

Primary endpoint: Overall response

Interventionalopen29 targetStarted 2020-11Completion 2027-028 sites · United StatesCity of Hope Medical Center

Pilot Trial of Leflunomide in Patients With High-Risk Smoldering Multiple Myeloma

NCT04370483Registry updated 2026-01-05·Early Phase 1
Active, not recruiting

Primary endpoint: Progressive disease

Interventionalopen1 targetStarted 2020-10Completion 2026-111 site · United StatesCity of Hope Medical Center