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hif2alpha inhibitor dff332

Generic: HIF2alpha Inhibitor DFF332

hif2alpha inhibitor dff332: 1 clinical trial tracked.

hif2alpha inhibitor dff332 evidence translation

What we can confirm

1 tracked trial

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
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Prepared research question

What is verified about hif2alpha inhibitor dff332, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

Clinical Trial Registry Records (1)

A Phase I/Ib, Open-label, Multi-center Study of DFF332 as a Single Agent and in Combination With Everolimus or IO Agents in Patients With Advanced/Relapsed ccRCC and Other Malignancies With HIF2α Stabilizing Mutations

NCT04895748Registry updated 2026-03-03·Phase 1
Terminated

Primary endpoint: Incidence and severity of adverse events (AEs) and serious adverse events (SAEs)

Interventionalopen40 targetStarted 2021-11Completion 2026-0211 sites · Czechia, France, Italy, Japan…Novartis Pharmaceuticals