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firmonertinib

firmonertinib: developed by 1 company · 2 clinical trials tracked.

firmonertinib evidence translation

What we can confirm

What it means

Source-backed records connect firmonertinib to AVBP; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could firmonertinib → AVBP affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence2 indications · 0 study sponsors

Related indications

Non-Small-Cell Lung Cancer; NSCLCNSCLC

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
ArriVent BioPharma, Inc. (AVBP)
Non-Small-Cell Lung Cancer; NSCLC
Phase 3
Clinical Trials (2)

A Global, Phase 3, Randomized, Multicenter, Open-Label Study to Evaluate the Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of Osimertinib or Afatinib as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic Non-Small-Cell Lung Cancer With Epidermal Growth Factor Receptor P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations (ALPACCA)

NCT07185997·Phase 3·AVBP
Recruiting

Primary endpoint: Progression Free Survival (PFS) determined by blinded independent central review (BICR)

InterventionalRandomizedopen480 targetStarted 2025-12Completion 2030-1250 sites · Australia, Canada, France, Greece…ArriVent BioPharma, Inc.

A Global Phase 3, Double-Blind, Randomized, Controlled Multicenter Study to Assess the Efficacy and Safety of Firmonertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB - IIIB NSCLC With Uncommon Epidermal Growth Factor Receptor (EGFR) Mutations, Following Complete Surgical Resection With or Without Adjuvant Chemotherapy (FIRMOST)

NCT07010419·Phase 3·AVBP
Recruiting

Primary endpoint: Disease free survival (DFS)

InterventionalRandomizedquadruple338 targetStarted 2025-05Completion 2032-042 sites · ChinaAllist Pharmaceuticals, Inc.

Frequently asked questions

Who is developing firmonertinib?

firmonertinib is being developed by ArriVent BioPharma, Inc..

How many clinical trials involve firmonertinib?

BioSniper tracks 2 clinical trials involving firmonertinib.