fenfluramine
fenfluramine: 4 clinical trials tracked.
fenfluramine evidence translation
What we can confirm
4 tracked trials
What it means
What to watch
Prepared research question
What is verified about fenfluramine, and what remains unknown?
Traceable citations · Unknowns marked
See linked entities and source evidence1 indications · 1 study sponsors
Related indications
Study sponsors
Clinical Trial Registry Records (4)
Using Fenfluramine to Test the Serotonin Deficiency Theory of Depression
Primary endpoint: Change in cortical [11C]Cimbi-36 non-displaceable binding potential (BPND) after dl-fenfluramine versus placebo (serotonin release capacity)
Open-Label, Single-Arm, Phase 3 Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less Than 2 Years of Age With Dravet Syndrome
Primary endpoint: Change from Baseline in QT interval corrected by Fridericia (QTcF) at Visit 13 (End of Treatment/Early Termination (EOT/ET))
Fenfluramine for the Treatment of Refractory Epilepsy in Adult Dravet Patients
Primary endpoint: Seizure reduction
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Fixed-Dose, Multicenter Study To Examine The Efficacy And Safety Of ZX008 In Subjects With CDKL5 Deficiency Disorder Followed By An Open-Label Extension
Primary endpoint: Percentage Change from Baseline in Countable Motor Seizure Frequency (CMSF) (Part 1)