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evinacumab

Generic: evinacumab·Brand: Evkeeza

evinacumab: developed by 1 company · 2 clinical trials tracked.

evinacumab evidence translation

What we can confirm

What it means

Source-backed records connect evinacumab to RARE; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could evinacumab → RARE affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence2 indications · 0 study sponsors

Related indications

Homozygous Familial Hypercholesterolemia (HoFH)Homozygous Familial Hypercholesterolemia

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
Ultragenyx Pharmaceutical Inc. (RARE)
Homozygous Familial Hypercholesterolemia (HoFH)
Approved
Clinical Trials (2)

A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamic Effects of ANGPTL3 Inhibition With Either Small-Interfering RNA Alone or in Combination With an ANGPTL3 Antibody in Participants With Diabetic Kidney Disease

NCT07271186·Phase 2
Recruiting

Primary endpoint: Percent change in Urine Albumin to Creatinine Ratio (UACR)

InterventionalRandomizedquadruple270 targetStarted 2026-01Completion 2028-0450 sites · United StatesRegeneron Pharmaceuticals

Safety and Effectiveness of Evinacumab for the Treatment of Homozygous Familial Hypercholesterolemia in a Real Life Setting in Canada

NCT05611528·Phase 3·RARE
Completed

Primary endpoint: Change in lipid profile

Interventionalopen10 enrolledStarted 2023-02Completion 2025-031 site · CanadaDaniel Gaudet

Frequently asked questions

Who is developing evinacumab?

evinacumab is being developed by Ultragenyx Pharmaceutical Inc..

How many clinical trials involve evinacumab?

BioSniper tracks 2 clinical trials involving evinacumab.