etrumadenant
etrumadenant: sourced relationships with 1 company · 12 clinical trials tracked.
etrumadenant evidence translation
What we can confirm
12 tracked trials
What it means
What to watch
Prepared research question
How could etrumadenant → RCUS affect its developer, and what evidence supports the link?
Traceable citations · Unknowns marked
See linked entities and source evidence8 indications · 1 study sponsors
Related indications
Study sponsors
Dated Pipeline Records (1)
| Company | Dated record stage |
|---|---|
| Arcus Biosciences, Inc. (RCUS) Healthy Participants; Oligometastatic Prostate Cancer; Non S… | Phase 2 |
Clinical Trial Registry Records (12)showing 10 most recent
A Phase 2, Open-Label, Multicenter, Randomized Study Evaluating Neoadjuvant Therapy Targeting the Adenosine Immunosuppressive Pathway in Combination With Immune Checkpoint Blockade and Radiation Therapy in Patients With Advanced PANCreatic Ductal Adenocarcinoma Who Are Candidates for Surgical Resection
Primary endpoint: Change in the number of intratumoral CD8+ T-cells
Phase II Single Arm Study Testing SBRT, Adenosine Signaling Modulation (AB680, AB928), and Immune Checkpoint Inhibition (AB122) for Men With Hormone Sensitive Oligometastatic Prostate Cancer
Primary endpoint: Biochemical recurrence-free survival at 12-months
A Phase 2 Platform Study Evaluating the Safety and Efficacy of Novel Treatment Combinations in Patients With Lung Cancer (VELOCITY-Lung)
Primary endpoint: Substudies 01 and 02: Objective Response Rate (ORR) as Assessed by the Investigator According to Response Evaluation Criteria in Solid Tumors (RECIST) Version 1.1
A Phase I-II Study to Test the Safety and Efficacy of PD1 (AB122) and Adenosine Receptor (AB928) Antagonists With Chemotherapy After Short-Course Radiation for Rectal Cancer.
Primary endpoint: Number of treated patients who achieve complete pathologic response
A Phase 1, Open-label, Randomized, Single-dose, Three-treatment, Three-way Crossover Pharmacokinetic Study to Evaluate the Relative Bioavailability of Etrumadenant (AB928) Tablet and Capsule Formulations and Food Effect on the Pharmacokinetics of the Tablet Formulation in Healthy Adult Participants
Primary endpoint: Maximum Observed Plasma Concentration (Cmax) of Etrumadenant
A Phase 2 Trial of SRF617 in Combination With AB928 (Etrumadenant) and AB122 (Zimberelimab) in Patients With Metastatic Castration-Resistant Prostate Cancer
Primary endpoint: Number of Participants With Response
A Pilot Study to Evaluate the Safety and Efficacy of Zimberelimab (AB122) in Combination With Domvanalimab (AB154) and Etrumadenant (AB928) in Patients With Previously Treated Non-Small Cell Lung Cancer
Primary endpoint: Objective response rate (ORR)
A Phase 1b/2, Open-Label, Randomized Platform Study Evaluating The Efficacy and Safety of AB928 Based Treatment Combinations in Patients With Metastatic Colorectal Cancer
Primary endpoint: Cohort A and B - Progression-free Survival (PFS)
A Phase 1b/2, Open-Label, Randomized Platform Study Evaluating the Efficacy and Safety of AB928-Based Treatment Combinations in Patients With Metastatic Castrate Resistant Prostate Cancer
Primary endpoint: Objective Response Rate (ORR) in Stage 1 and 2
A Phase 2 Study to Evaluate the Safety and Efficacy of AB122 Monotherapy, AB154 in Combination With AB122, and AB154 in Combination With AB122 and AB928 in Front-Line, Non-Small Cell Lung Cancer
Primary endpoint: Objective response rate (ORR)
Frequently asked questions
Which companies have sourced relationships with etrumadenant?
etrumadenant has dated SEC/FDA relationship records for Arcus Biosciences, Inc..
How many clinical trials involve etrumadenant?
BioSniper tracks 12 clinical trials involving etrumadenant.