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etrasimod

Generic: etrasimod·Brand: Velsipity

etrasimod: developed by 1 company · 7 clinical trials tracked.

etrasimod evidence translation

What we can confirm

What it means

Source-backed records connect etrasimod to ARNA; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could etrasimod → ARNA affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence3 indications · 2 study sponsors
Development Pipeline (1)
Clinical Trials (7)

Etrasimod as Primary and Secondary Prevention of Pouchitis (ESPIRIT)

NCT07486921·Phase 2·MAIA
Recruiting

Primary endpoint: Proportion of participants with at least 1 episode of acute pouchitis

InterventionalRandomizedsingle40 targetStarted 2026-06Completion 2030-021 site · United StatesMaia Kayal

A PHASE 2 OPEN-LABEL, SINGLE ARM STUDY TO EVALUATE THE EFFICACY, PHARMACOKINETICS, AND SAFETY OF ETRASIMOD IN PEDIATRIC PARTICIPANTS WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS

NCT07470879·Phase 2·PFE
Recruiting

Primary endpoint: Number and percent of enrolled participants with clinical remission based on Modified Mayo Score (MMS) at Week 52

Interventionalopen24 targetStarted 2026-05Completion 2034-0825 sites · Canada, France, Germany, Israel…Pfizer

Effectiveness of Etrasimod on Disease Activity and Patient-reported Outcomes in Ulcerative Colitis - EFFECT-UC

Recruiting

Primary endpoint: Proportion of patients with symptomatic remission

Observational360 targetStarted 2024-05Completion 2026-0638 sites · Canada, Germany, United KingdomPfizer

An Open-Label, Single-Arm Study to Evaluate the Efficacy, Pharmacokinetics, and Safety of Etrasimod in Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

NCT05287126·Phase 2·PFE
Recruiting

Primary endpoint: Proportion of Participants Achieving Clinical Remission as Assessed by Modified Mayo Score (MMS) at Week 52

Interventionalopen36 targetStarted 2022-12Completion 2033-0746 sites · Belgium, Japan, Poland, Slovakia…Pfizer

A Randomized, Double Blind, Placebo Controlled, 52 Week Study to Assess the Efficacy and Safety of Etrasimod in Subjects With Moderately Active Ulcerative Colitis

NCT04607837·Phase 2·PFE
Completed

Primary endpoint: Percentage of Participants Achieving Clinical Remission (CR) at Week 52 Using Modified Mayo Score (MMS)

InterventionalRandomizeddouble234 enrolledStarted 2021-04Completion 2024-0650 sites · United StatesPfizer

A Multicenter, Randomized, Double-Blind, Parallel-Group Study to Assess the Efficacy and Safety of Oral Etrasimod as Induction and Maintenance Therapy for Moderately to Severely Active Crohn's Disease

NCT04173273·Phase 2/Phase 3·PFE
Terminated

Primary endpoint: Percentage of Participants With Endoscopic Response by Simple Endoscopic Score in Crohn's Disease (SES-CD) at Week 14: SSA

InterventionalRandomizeddouble379 targetStarted 2020-01Completion 2025-0650 sites · United StatesPfizer

An Open-Label Extension Study of Etrasimod in Subjects With Moderately to Severely Active Ulcerative Colitis

NCT03950232·Phase 3·PFE
Active, not recruiting

Primary endpoint: Number and Severity of Safety Measures

Interventionalopen896 targetStarted 2019-09Completion 2029-0650 sites · United StatesPfizer

Frequently asked questions

Who is developing etrasimod?

etrasimod is being developed by ARENA PHARMACEUTICALS INC.

How many clinical trials involve etrasimod?

BioSniper tracks 7 clinical trials involving etrasimod.