esketamine
esketamine: 3 clinical trials tracked.
esketamine evidence translation
What we can confirm
3 tracked trials
What it means
What to watch
Prepared research question
What is verified about esketamine, and what remains unknown?
Traceable citations · Unknowns marked
See linked entities and source evidence0 indications · 2 study sponsors
Related indications
No linked indication is available.
Clinical Trials (3)
A Randomized, Double-blind, Multicenter, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant Depression
Primary endpoint: Double-Blind (DB) Treatment Phase: Change From Baseline in Montgomery-Asberg Depression Rating Scale (MADRS) Total Score From Day 1 to the End of the 4-Week Double-Blind Treatment Phase
Effect of Esketamine on Postoperative Sleep in Postmenopausal Women
Primary endpoint: The incidence of postoperative sleep disturbance (PSD) on postoperative day 1.
A Double-blind, Randomized, Psychoactive Placebo-controlled Study to Evaluate the Efficacy and Safety of Intranasal Esketamine 84 mg in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder in Adolescent Participants With Acute Suicidal Ideation or Behavior
Primary endpoint: Change from Baseline in Depressive Symptoms Measured by Children's Depression Rating Scale - Revised (CDRS-R) Total Score at 24 Hours Post First Dose