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egfr/cd3-targeting t-cell engaging molecule tak-186

Generic: EGFR/CD3-targeting T-cell Engaging Molecule TAK-186

egfr/cd3-targeting t-cell engaging molecule tak-186: 1 clinical trial tracked.

egfr/cd3-targeting t-cell engaging molecule tak-186 evidence translation

What we can confirm

1 tracked trial

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about egfr/cd3-targeting t-cell engaging molecule tak-186, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence1 indications · 0 study sponsors

Related indications

Study sponsors

No additional listed-company sponsor is linked.

Clinical Trial Registry Records (1)

A Phase 1/2, First-in-Human, Open-Label, Dose-Escalation Study of TAK-186 (Also Known as MVC-101), An EGFR x CD3 COnditional Bispecific Redirected Activation (COBRA) Protein in Patients With Unresectable Locally Advanced or Metastatic Cancer

NCT04844073Registry updated 2025-12-04·Phase 1/Phase 2
Terminated

Primary endpoint: Number of Participants with Treatment Emergent Adverse Events (TEAEs)

Interventionalopen95 targetStarted 2021-03Completion 2025-0627 sites · Australia, South Korea, United Kingdom, United StatesTakeda