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dexmedetomidine

Generic: DEXMEDETOMIDINE HYDROCHLORIDE·Brand: DEXMEDETOMIDINE HYDROCHLORIDE, Dexased, Dexdomitor, Dexmedesed, Dexmedvet, IGALMI, Igalmi, PRECEDEX, Precedex, Sedexodine, Sileo·Code: BXCL501

dexmedetomidine: sourced relationships with 1 company · 23 clinical trials tracked.

dexmedetomidine evidence translation

What we can confirm

What it means

Source-backed records connect dexmedetomidine to BTAI; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could dexmedetomidine → BTAI affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence8 indications · 0 study sponsors

Study sponsors

No additional listed-company sponsor is linked.

Dated Pipeline Records (1)
CompanyDated record stage
BioXcel Therapeutics, Inc. (BTAI)
developer · Reported 2026-03-27 · Current development: unknownSource
Agitation; Agitation,Psychomotor
Phase 3
Clinical Trial Registry Records (23)showing 10 most recent

An Alpha2-adrenoceptor Agonist to Reduce Locus Coeruleus Activity During Sleep in Adults With Insomnia Disorder: a Pilot Randomised Placebo-controlled Cross-over Study

NCT07392177Registry updated 2026-08-19·Phase 2
Recruiting

Primary endpoint: Electrographic (EEG) signatures

InterventionalRandomizedquadruple15 targetStarted 2026-08Completion 2027-031 site · AustraliaWoolcock Institute of Medical Research

Evaluation of an Opioid-Free Approach in Sedation Method Selection in Endoscopy Units: A Prospective Randomized Observational Double-Blind Comparison of Dexmedetomidine (Opioid-Free) and Remifentanil-Dexmedetomidine (Opioid-Based) Combination

NCT07649746Registry updated 2026-06-16·N/A
Not yet recruiting

Primary endpoint: Incidence of Opioid-Related Adverse Symptoms

InterventionalRandomizedquadruple80 targetStarted 2026-06Completion 2028-02Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With a Sublingual Formulation of Dexmedetomidine (BXCL501)

NCT06943404Registry updated 2026-04-14·Phase 2
Recruiting

Primary endpoint: Change in ASD Score

InterventionalRandomizedquadruple100 targetStarted 2026-02Completion 2026-093 sites · United StatesUniversity of North Carolina, Chapel Hill

Dexmedetomidine Versus Fentanyl-Midazolam Combination to Attenuate the Stress Response in Laparoscopic Cholecystectomy

NCT07425444Registry updated 2026-02-20·Phase 4
Not yet recruiting

Primary endpoint: Hemodynamics

InterventionalRandomizeddouble50 targetStarted 2026-02Completion 2027-04Assiut University

A Randomized Comparison Between 0.67 mcg/kg, 1 mcg/kg, and 1.33 mcg/kg of Perineural Dexmedetomidine for Ultrasound-Guided Infraclavicular Block

NCT07249827Registry updated 2026-07-07·Phase 2
Completed

Primary endpoint: Motor block duration

InterventionalRandomizedquadruple69 enrolledStarted 2025-12Completion 2026-061 site · CanadaMcGill University Health Centre/Research Institute of the McGill University Health Centre

Differences in C-Reactive Protein Levels Between Traumatic Brain Injury Patients Receiving Dexmedetomidine and Those Not Receiving Dexmedetomidine Undergoing Craniotomy at Prof. Dr. Margono Soekarjo Regional General Hospital, Purwokerto

NCT07406555Registry updated 2026-02-17·Phase 4
Completed

Primary endpoint: Change in C-Reactive Protein (CRP) Levels

InterventionalRandomizedtriple25 enrolledStarted 2025-10Completion 2025-111 site · IndonesiaUniversitas Jenderal Soedirman

Efficacy of Dexmedetomidine Versus Midazolam Sedation on Extubation Time in Mechanically Ventilated Preterm Infants: a Randomized Controlled Multicenter Trial - DEXPRE

NCT06878703Registry updated 2026-02-10·Phase 3
Recruiting

Primary endpoint: Time, measured in minutes, is evaluated from the discontinuation of the experimental treatment (either dexmedetomidine-based or midazolam-based sedation) to extubation.

InterventionalRandomizedquadruple380 targetStarted 2025-10Completion 2029-101 site · FranceAssistance Publique - Hôpitaux de Paris

Study Evaluating Dexmedetomidine in the Acute Treatment of Electrical Storm: Outpatient Follow-up of Mental Health INDices (SDATE OF MIND)

NCT07368062Registry updated 2026-07-01
Recruiting

Primary endpoint: Post-traumatic stress disorder symptoms

Observational70 targetStarted 2025-03Completion 2028-061 site · CanadaOttawa Heart Institute Research Corporation

Dexmedetomidine as an Adjuvant to Bupivacaine in Bilateral Pectoral Nerve Blocks for Postoperative Pain Control After Cardiac Surgeries: A Randomized Controlled Trial

NCT06453681Registry updated 2026-02-19·Phase 4
Completed

Primary endpoint: The duration of analgesia

InterventionalRandomizedquadruple60 enrolledStarted 2024-08Completion 2025-052 sites · EgyptKasr El Aini Hospital

Study Evaluating Dexmedetomidine in the Acute Treatment of Electrical Storm

NCT06281977Registry updated 2026-07-07·Phase 3
Recruiting

Primary endpoint: The primary outcome is a composite of the following: 1. All-cause in-hospital death AND/OR 2. Any in-hospital ventricular arrhythmia requiring treatment after study drug initiation.

InterventionalRandomizedtriple192 targetStarted 2024-05Completion 2027-082 sites · Canada, United StatesOttawa Heart Institute Research Corporation

Frequently asked questions

Which companies have sourced relationships with dexmedetomidine?

dexmedetomidine has dated SEC/FDA relationship records for BioXcel Therapeutics, Inc..

How many clinical trials involve dexmedetomidine?

BioSniper tracks 23 clinical trials involving dexmedetomidine.