deupirfenidone
deupirfenidone: 3 clinical trials tracked.
deupirfenidone evidence translation
What we can confirm
3 tracked trials
What it means
What to watch
Prepared research question
What is verified about deupirfenidone, and what remains unknown?
Traceable citations · Unknowns marked
See linked entities and source evidence1 indications · 0 study sponsors
Related indications
Study sponsors
No additional listed-company sponsor is linked.
Clinical Trial Registry Records (3)
A Randomized, Double-Blind, Head-to-Head Phase 3 Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to Pirfenidone at 52 Weeks in Adults With Idiopathic Pulmonary Fibrosis (SURPASS-IPF)
Primary endpoint: Absolute change in forced vital capacity (FVC) measured in mL
A Randomized Double-blind, Four-Arm Active and Placebo-controlled Dose-Finding Trial to Evaluate the Efficacy, Tolerability, Safety and Dose Response of LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Primary endpoint: Rate of decline in Forced Vital Capacity over 26 weeks (Part A)
A Phase 1, Double-Blind, Randomized, Crossover Study in Older Healthy Subjects to Compare the Safety, Tolerability, and Pharmacokinetics of Lyt-100 (Deupirfenidone) to Pirfenidone
Primary endpoint: Part 1: Cmax of BID deupirfenidone versus TID pirfenidone