Skip to main content

cretostimogene grenadenorepvec

Generic: Cretostimogene Grenadenorepvec

cretostimogene grenadenorepvec: developed by 1 company · 6 clinical trials tracked.

cretostimogene grenadenorepvec evidence translation

What we can confirm

6 tracked trials

What it means

Source-backed records connect cretostimogene grenadenorepvec to CGON; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could cretostimogene grenadenorepvec → CGON affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence4 indications · 1 study sponsors

Related indications

Non-Muscle Invasive Bladder Cancer; Non Muscle Invasive Bladder Cancer; High-Risk Non-Muscle-Invasive Bladder CancerBladder CancerUrologic CancerUrothelial Carcinoma
Development Pipeline (1)
CompanyPhase
CG Oncology, Inc. (CGON)
Non-Muscle Invasive Bladder Cancer; Non Muscle Invasive Blad…
Phase 2
Clinical Trials (6)

An Expanded Access Program of Cretostimogene Grenadenorepvec in Patients With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Bacillus Calmette-Guerin (BCG)

Available
Expanded Access26 sites · United StatesCG Oncology, Inc.

A Phase 2, Multi-Arm, Multi-Cohort, Open-Label Study to Evaluate the Safety and Efficacy of Cretostimogene Grenadenorepvec in Participants With High-Risk Non-Muscle-Invasive Bladder Cancer (NMIBC)

NCT06567743·Phase 2·CGON
Recruiting

Primary endpoint: Cohort A (Arm 1 and 2): Complete response rate

InterventionalRandomizedopen325 targetStarted 2024-09Completion 2027-1250 sites · United StatesCG Oncology, Inc.

A Phase 1b, Single Arm Study of CG0070 After Transurethral Resection in Patients With Intermediate Risk Non-Muscle Invasive Bladder Cancer (IR NMIBC)

NCT06253845·Phase 1·GHRS
Active, not recruiting

Primary endpoint: Incidence of Treatment-Emergent Adverse Events

Interventionalopen20 targetStarted 2024-03Completion 2027-091 site · United StatesH. Lee Moffitt Cancer Center and Research Institute

A Phase 3, Randomized Study of Adjuvant Cretostimogene Grenadenorepvec Versus Observation for the Treatment of Intermediate Risk Non-Muscle Invasive Bladder Cancer (IR-NMIBC) Following Transurethral Resection of Bladder Tumor (TURBT)

NCT06111235·Phase 3·CGON
Active, not recruiting

Primary endpoint: Recurrence Free Survival (RFS)

InterventionalRandomizedopen367 targetStarted 2023-12Completion 2029-0250 sites · United StatesCG Oncology, Inc.

A Phase 3 Study of Cretostimogene Grenadenorepvec in Patients With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Bacillus-Calmette-Guerin (BCG)

NCT04452591·Phase 3·CGON
Active, not recruiting

Primary endpoint: Cohort C:

Interventionalopen190 targetStarted 2020-10Completion 2031-1250 sites · Australia, Canada, United StatesCG Oncology, Inc.

A Phase 1 Study of CG0070 Combined With Nivolumab in Cisplatin Ineligible Patients With Muscle Invasive Bladder Cancer (MIBC)

NCT04610671·Phase 1
Completed

Primary endpoint: Incidence of Treatment-Emergent Adverse Events

Interventionalopen21 enrolledStarted 2020-10Completion 2024-071 site · United StatesH. Lee Moffitt Cancer Center and Research Institute

Frequently asked questions

Who is developing cretostimogene grenadenorepvec?

cretostimogene grenadenorepvec is being developed by CG Oncology, Inc..

How many clinical trials involve cretostimogene grenadenorepvec?

BioSniper tracks 6 clinical trials involving cretostimogene grenadenorepvec.