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chlorambucil

Generic: CHLORAMBUCIL·Brand: LEUKERAN

chlorambucil: 4 clinical trials tracked.

chlorambucil evidence translation

What we can confirm

4 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about chlorambucil, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence1 indications · 2 study sponsors
Clinical Trial Registry Records (4)

A Phase 3, Open-Label, Randomized Study of BGB-16673 Compared to Investigator's Choice in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Covalent BTK Inhibitors

NCT06970743Registry updated 2026-08-24·Phase 3·ONC
Active, not recruiting

Primary endpoint: Progression-Free Survival (PFS) by IRC

InterventionalRandomizedopen153 enrolledStarted 2025-05Completion 2029-1150 sites · ChinaBeOne Medicines

A Global Multicenter Open Label Randomized Phase III Confirmatory Study of Lisaftoclax (APG-2575) in Combination With Acalabrutinib vs Immunochemotherapy in Patients With Newly Diagnosed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

NCT06319456Registry updated 2026-07-28·Phase 3
Recruiting

Primary endpoint: Progress Free Survival (PFS)

InterventionalRandomizedopen344 targetStarted 2024-04Completion 2028-0810 sites · ChinaAscentage Pharma Group Inc.

A Randomized, Multicenter, Open-Label, Phase 3 Study to Evaluate the Efficacy and Safety of Acalabrutinib Versus Chlorambucil Plus Rituximab in Subjects With Previously Untreated Chronic Lymphocytic Leukemia

NCT04075292Registry updated 2026-09-14·Phase 3·AZN
Active, not recruiting

Primary endpoint: Progression Free Survival (PFS) Assessed by BICR

InterventionalRandomizedopen155 enrolledStarted 2020-01Completion 2027-0146 sites · China, Philippines, Taiwan, Thailand…AstraZeneca

A Randomized, Open-label, Phase 3 Study of the Combination of Ibrutinib Plus Venetoclax Versus Chlorambucil Plus Obinutuzumab for the First-line Treatment of Subjects With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL).

NCT03462719Registry updated 2026-09-28·Phase 3
Active, not recruiting

Primary endpoint: Progression Free Survival (PFS)

InterventionalRandomizedopen211 enrolledStarted 2018-04Completion 2029-0450 sites · Belgium, Canada, Czechia, Denmark…Janssen Research & Development, LLC