Skip to main content

cemacabtagene ansegedleucel

Generic: Cemacabtagene Ansegedleucel

cemacabtagene ansegedleucel: developed by 1 company · 3 clinical trials tracked.

cemacabtagene ansegedleucel evidence translation

What we can confirm

What it means

Source-backed records connect cemacabtagene ansegedleucel to ALLO; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could cemacabtagene ansegedleucel → ALLO affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence1 indications · 0 study sponsors

Related indications

Large B-cell Lymphoma

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
Allogene Therapeutics, Inc. (ALLO)
Large B-cell Lymphoma
Phase 3
Clinical Trials (3)

A Randomized, Open-label Study Evaluating the Efficacy and Safety of Cemacabtagene Ansegedleucel in Participants With Minimal Residual Disease After Response to First Line Therapy for Large B-cell Lymphoma

NCT06500273·Phase 2·ALLO
Recruiting

Primary endpoint: Event-free survival per independent review committee assessment

InterventionalRandomizedopen250 targetStarted 2024-06Completion 2032-1250 sites · United StatesAllogene Therapeutics

A Randomized, Open-Label, Phase 2 Study Evaluating Lymphodepletion With ALLO-647, Fludarabine, and Cyclophosphamide, vs. Fludarabine and Cyclophosphamide Alone, in Subjects With Relapsed/Refractory Large B-Cell Lymphoma Receiving ALLO-501A Allogeneic CAR T Cell Therapy

NCT05714345·Phase 2·ALLO
Terminated

Primary endpoint: Progression-Free Survival (PFS) of a Lymphodepletion Regimen Containing FCA vs FC Alone Per Independent Review Committee

InterventionalRandomizedopen2 targetStarted 2023-11Completion 2024-102 sites · Belgium, United StatesAllogene Therapeutics

A Single-Arm, Open-Label, Phase 1/2 Study Evaluating the Safety, Efficacy, and Cellular Kinetics/Pharmacodynamics of ALLO-501A, an Anti-CD19 Allogeneic CAR T Cell Therapy, and ALLO-647, an Anti-CD52 Monoclonal Antibody, in Subjects With Relapsed/Refractory Large B-Cell Lymphoma (LBCL)

NCT04416984·Phase 1/Phase 2·ALLO
Active, not recruiting

Primary endpoint: Phase 1a: Proportion of subjects experiencing Dose Limiting Toxicities (DLT) at increasing doses of ALLO-501A

Interventionalopen160 targetStarted 2020-05Completion 2029-0529 sites · Australia, Canada, United StatesAllogene Therapeutics

Frequently asked questions

Who is developing cemacabtagene ansegedleucel?

cemacabtagene ansegedleucel is being developed by Allogene Therapeutics, Inc..

How many clinical trials involve cemacabtagene ansegedleucel?

BioSniper tracks 3 clinical trials involving cemacabtagene ansegedleucel.