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breyanzi

Generic: lisocabtagene maraleucel·Brand: Breyanzi

breyanzi: 8 clinical trials tracked.

breyanzi evidence translation

What we can confirm

8 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
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Prepared research question

What is verified about breyanzi, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence3 indications · 2 study sponsors
Clinical Trials (8)

Phase 2 Study of Glofitamab and Gemcitabine and Oxaliplatin (Glofit-GemOx) Bridging to Lisocabtagene Maraleucel in Relapsed/Refractory Aggressive B-cell Lymphomas

NCT07711483·Phase 2
Not yet recruiting

Primary endpoint: Complete Response Rate (CRR) to lisocabtagene maraleucel

Interventionalopen56 targetStarted 2026-10Completion 2030-102 sites · United StatesMassachusetts General Hospital

Safety and Efficacy of the Addition of Nemtabrutinib to Lisocabtagene Maraleucel in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia

NCT07194980·Phase 2
Recruiting

Primary endpoint: Complete response (CR)

Interventionalopen20 targetStarted 2026-09Completion 2029-101 site · United StatesFred Hutchinson Cancer Center

Non-interventional Cohort Study of Patients Treated With Liso-Cel (Lisocabtagene Maraleucel) for Relapsed/Refractory Marginal Zone Lymphoma in the Postmarketing Setting

Active, not recruiting

Primary endpoint: Incidence and severity of selected adverse events after lisocabtagene maraleucel infusion

Observational300 targetStarted 2026-03Completion 2048-031 site · United StatesBristol-Myers Squibb

A Phase 3 Randomized Controlled Trial of Rondecabtagene Autoleucel , an Autologous, Dual-targeting CD19/CD20 CAR T-Cell Product Candidate, Vs. Investigator's Choice of CD19 CAR T-Cell Therapy in Patients With Relapsed or Refractory Large B-Cell Lymphoma in the Second-line Setting

NCT07188558·Phase 3·LYEL
Recruiting

Primary endpoint: Event free survival

InterventionalRandomizedopen400 targetStarted 2026-01Completion 2032-0136 sites · United StatesLyell Immunopharma, Inc.

A Phase II Study Evaluating the Safety and Efficacy of the Combination of Zanubrutinib Plus Lisocabtagene Maraleucel for Richter's Syndrome

NCT05873712·Phase 2
Recruiting

Primary endpoint: Overall response rate

Interventionalopen24 targetStarted 2023-07Completion 2026-123 sites · United StatesAseel Alsouqi

Phase 2 Study of the Combination of Lisocabtagene Maraleucel, Nivolumab, and Ibrutinib in Richter's Transformation

NCT05672173·Phase 2
Active, not recruiting

Primary endpoint: Complete Response (CR)

Interventionalopen9 targetStarted 2023-06Completion 2026-092 sites · United StatesCity of Hope Medical Center

A Phase Ib Open-Label Study Evaluating the Safety and Efficacy of NKTR-255 in Combination With CD19-Directed CAR-T Cell Therapy in Patients With Relapsed/Refractory (R/R) Large B-Cell Lymphoma (LBCL)

NCT05359211·Phase 1
Active, not recruiting

Primary endpoint: Incidence of adverse events (AEs)

Interventionalopen27 targetStarted 2022-12Completion 2026-091 site · United StatesFred Hutchinson Cancer Center

A Phase 1b Study Evaluating the Safety, Tolerability and Preliminary Anti-tumor Activity of NT-I7 a Long-acting Human IL-7, Post-Kymriah®, Post-Yescarta®, or Post-Breyanzi® in Subjects With Relapsed/Refractory Large B-cell Lymphoma

NCT05075603·Phase 1
Completed

Primary endpoint: Incidence, Nature, and Severity of Adverse Events, Graded According to NCI CTCAE v5.0, Except for Cytokine Release Syndrome (CRS) and Immune Effector Cell-associated Neurotoxicity Syndrome (ICANS), Which Were Graded Based on ASTCT Guidelines

Interventionalopen17 enrolledStarted 2021-07Completion 2025-033 sites · United StatesNeoImmuneTech