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bivamelagon

Generic: Bivamelagon·Code: LB54640

bivamelagon: developed by 1 company · 2 clinical trials tracked.

bivamelagon evidence translation

What we can confirm

What it means

Source-backed records connect bivamelagon to RYTM; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could bivamelagon → RYTM affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence1 indications · 0 study sponsors

Related indications

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (2)
Clinical Trials (2)

A Long-Term, Open-Label Extension Study of Bivamelagon in Participants With Hypothalamic Obesity (HO)

NCT07156578·Phase 2·RYTM
Enrolling by invitation

Primary endpoint: Safety and tolerability of bivamelagon as assessed by the number and frequency of AEs

Interventionalopen25 targetStarted 2025-11Completion 2028-049 sites · United Kingdom, United StatesRhythm Pharmaceuticals, Inc.

A Randomized, Placebo-controlled, Double-Blind Phase 2 Study to Assess Efficacy and Safety of LB54640 in Patients With Hypothalamic Obesity, With an Open-Label Extension

NCT06046443·Phase 2·RYTM
Completed

Primary endpoint: Mean percentage change in BMI

InterventionalRandomizedtriple28 enrolledStarted 2024-07Completion 2026-0210 sites · United Kingdom, United StatesRhythm Pharmaceuticals, Inc.

Frequently asked questions

Who is developing bivamelagon?

bivamelagon is being developed by RHYTHM PHARMACEUTICALS, INC..

How many clinical trials involve bivamelagon?

BioSniper tracks 2 clinical trials involving bivamelagon.