bion-1301
bion-1301: sourced relationships with 1 company · 5 clinical trials tracked.
bion-1301 evidence translation
What we can confirm
5 tracked trials
What it means
What to watch
Prepared research question
How could bion-1301 → KDNY affect its developer, and what evidence supports the link?
Traceable citations · Unknowns marked
See linked entities and source evidence3 indications · 0 study sponsors
Related indications
Study sponsors
No additional listed-company sponsor is linked.
Dated Pipeline Records (1)
| Company | Dated record stage |
|---|---|
| CHINOOK THERAPEUTICS, INC. (KDNY) IgA nephropathy (IgAN) | Phase 1/Phase 2 |
Clinical Trial Registry Records (5)
A Phase IIIb, Multi-center, Two-arm, Randomized, Double-blind, Parallel Group Study to Evaluate the Efficacy and Safety of Zigakibart and Atrasentan Versus Zigakibart and Placebo in Patients With Primary IgA Nephropathy
Primary endpoint: Change in proteinuria from Baseline to Week 36, based on 24 hour urine collection
An Open-label, Multicenter Study to Assess the Effect of Zigakibart Treatment on Histologic, Circulating, and Excreted Markers of Kidney Disease and Dysfunction in Adult Patients With IgA Nephropathy.
Primary endpoint: Change in mesangial IgA deposition
A Multicenter Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Zigakibart in Adults With Primary IgA Nephropathy.
Primary endpoint: Number of participants with adverse events.
A Phase 3, Randomized, Double-blind, Placebo-controlled Study of BION-1301 in Adults With IgA Nephropathy (The BEYOND Study)
Primary endpoint: Change from baseline in eGFR
A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Atrasentan in Patients With IgA Nephropathy at Risk of Progressive Loss of Renal Function
Primary endpoint: Double-blind period: Change in proteinuria
Frequently asked questions
Which companies have sourced relationships with bion-1301?
bion-1301 has dated SEC/FDA relationship records for CHINOOK THERAPEUTICS, INC..
How many clinical trials involve bion-1301?
BioSniper tracks 5 clinical trials involving bion-1301.