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bexotegrast

Generic: Bexotegrast

bexotegrast: developed by 1 company · 3 clinical trials tracked.

bexotegrast evidence translation

What we can confirm

What it means

Source-backed records connect bexotegrast to PLRX; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could bexotegrast → PLRX affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence3 indications · 0 study sponsors

Related indications

Idiopathic Pulmonary Fibrosis; Primary Sclerosing CholangitisIdiopathic Pulmonary FibrosisPrimary Sclerosing Cholangitis

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
PLIANT THERAPEUTICS, INC. (PLRX)
Idiopathic Pulmonary Fibrosis; Primary Sclerosing Cholangiti…
Phase 2
Clinical Trials (3)

A Randomized, Double-blind, Dose-ranging, Placebo-controlled Study to Evaluate the Efficacy and Safety of Bexotegrast (PLN-74809) for the Treatment of Idiopathic Pulmonary Fibrosis (BEACON-IPF)

NCT06097260·Phase 2·PLRX
Terminated

Primary endpoint: Change From Baseline in Forced Vital Capacity at Week 52

InterventionalRandomizedquadruple320 enrolledStarted 2023-11Completion 2025-0450 sites · United StatesPliant Therapeutics, Inc.

A Phase 2a, Randomized, Double-Blind, Placebo-Controlled, Evaluation of PLN-74809 on Type 1 Collagen Deposition Using 68Ga-CBP8 PET/MRI Imaging in Participants With Idiopathic Pulmonary Fibrosis (IPF)

NCT05621252·Phase 2·PLRX
Completed

Primary endpoint: Primary Outcome

InterventionalRandomizeddouble10 enrolledStarted 2022-07Completion 2024-011 site · United StatesPliant Therapeutics, Inc.

A Randomized, Double-blind, Dose-ranging, Placebo-controlled, Phase 2a Evaluation of the Safety, Tolerability, and Pharmacokinetics of PLN-74809 in Participants With Primary Sclerosing Cholangitis (PSC) and Suspected Liver Fibrosis (INTEGRIS-PSC)

NCT04480840·Phase 2·PLRX
Completed

Primary endpoint: Number of Participants With Treatment Emergent Adverse Events

InterventionalRandomizedquadruple121 enrolledStarted 2020-07Completion 2024-0350 sites · Australia, Austria, Belgium, Canada…Pliant Therapeutics, Inc.

Frequently asked questions

Who is developing bexotegrast?

bexotegrast is being developed by PLIANT THERAPEUTICS, INC..

How many clinical trials involve bexotegrast?

BioSniper tracks 3 clinical trials involving bexotegrast.