Skip to main content

baxdrostat

·Code: CIN-107

baxdrostat: developed by 1 company · 7 clinical trials tracked.

baxdrostat evidence translation

What we can confirm

What it means

Source-backed records connect baxdrostat to CINC; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could baxdrostat → CINC affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence3 indications · 1 study sponsors
Development Pipeline (1)
Clinical Trials (7)

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effect of Baxdrostat on Ambulatory Blood Pressure in Chinese Participants With Uncontrolled Hypertension on Two or More Antihypertensive Medications Without Diuretics

NCT07686120·Phase 3·AZN
Not yet recruiting

Primary endpoint: Change from baseline in ambulatory 24-hour average Systolic blood pressure(SBP) at Week 12

InterventionalRandomizedquadruple286 targetStarted 2026-09Completion 2028-02AstraZeneca

A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effects of Baxdrostat on Ventricular Remodeling

NCT07655362·Phase 3
Not yet recruiting

Primary endpoint: Left Ventricular Mass indexed to baseline body surface area (LVMi)

InterventionalRandomizedquadruple286 targetStarted 2026-06Completion 2028-122 sites · CanadaSubodh Verma

A Randomised, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy and Safety of Baxdrostat in Adult Participants With Primary Aldosteronism

NCT07007793·Phase 3·AZN
Recruiting

Primary endpoint: Change from baseline in seated Systolic Blood Pressure (SBP) at Week 8

InterventionalRandomizedquadruple250 targetStarted 2025-08Completion 2028-0850 sites · Australia, Canada, China, France…AstraZeneca

A Phase III, Randomised, Placebo-controlled, Event-driven Study to Evaluate the Effect of Baxdrostat in Combination With Dapagliflozin Compared With Dapagliflozin Alone on the Risk of Incident Heart Failure and Cardiovascular Death

NCT06677060·Phase 3·AZN
Recruiting

Primary endpoint: To determine if baxdrostat/dapagliflozin is superior to placebo/dapagliflozin in reducing the risk of an HF event or CV death

InterventionalRandomizedquadruple11,300 targetStarted 2025-03Completion 2029-1250 sites · United StatesAstraZeneca

A Double-Blind, Randomised, Placebo-Controlled, Multicentre Study Evaluating the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension

NCT06344104·Phase 3·AZN
Completed

Primary endpoint: Change from baseline in seated SBP at Week 12

InterventionalRandomizedquadruple326 enrolledStarted 2024-04Completion 2026-0450 sites · Argentina, Australia, ChinaAstraZeneca

A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Assess the Effect of Baxdrostat on Ambulatory Blood Pressure in Participants With Resistant Hypertension

NCT06168409·Phase 3·AZN
Completed

Primary endpoint: Least Square Mean Difference for Change From Baseline in Ambulatory 24-hour Average SBP at Week 12: Treatment Policy Strategy

InterventionalRandomizedquadruple218 enrolledStarted 2024-03Completion 2025-0850 sites · Argentina, Australia, Belgium, Bulgaria…AstraZeneca

A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study to Assess the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension

NCT06034743·Phase 3·AZN
Completed

Primary endpoint: Change From Baseline in Seated Systolic Blood Pressure for 2 mg Baxdrostat

InterventionalRandomizedquadruple796 enrolledStarted 2023-11Completion 2025-1050 sites · Argentina, United StatesAstraZeneca

Frequently asked questions

Who is developing baxdrostat?

baxdrostat is being developed by CinCor Pharma, Inc..

How many clinical trials involve baxdrostat?

BioSniper tracks 7 clinical trials involving baxdrostat.