apitegromab
apitegromab: sourced relationships with 1 company · 5 clinical trials tracked.
apitegromab evidence translation
What we can confirm
5 tracked trials
What it means
What to watch
Prepared research question
How could apitegromab → SRRK affect its developer, and what evidence supports the link?
Traceable citations · Unknowns marked
See linked entities and source evidence3 indications · 0 study sponsors
Related indications
Study sponsors
No additional listed-company sponsor is linked.
Dated Pipeline Records (1)
| Company | Dated record stage |
|---|---|
| Scholar Rock Holding Corp (SRRK) SMA; Spinal Muscular Atrophy; Facioscapulohumeral Muscular D… | Phase 3 |
Clinical Trial Registry Records (5)
Expanded Access Protocol of Apitegromab for Patients With Spinal Muscular Atrophy
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter, 52-Week Study Evaluating the Efficacy and Safety of Apitegromab in Participants With Facioscapulohumeral Muscular Dystrophy (FORGE)
Primary endpoint: Assess the efficacy of apitegromab compared with placebo in participants with FSHD
A Phase 2, Double-Blind Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Efficacy, and Safety of Apitegromab in Subjects <2 Years Old With Spinal Muscular Atrophy (SMA)
Primary endpoint: Evaluate the PK of apitegromab in subjects <2 years old with SMA
A Phase 2 Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Apitegromab in Overweight and Obese Adult Subjects
Primary endpoint: Change from Baseline in total Lean Body Mass (kg) at 24 weeks
Phase 3, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Apitegromab (SRK-015) in Patients With Later-Onset Spinal Muscular Atrophy Receiving Background Nusinersen or Risdiplam Therapy
Primary endpoint: Main Efficacy Population: Change from Baseline in Hammersmith Functional Motor Scale Expanded (HFMSE) total score.
Frequently asked questions
Which companies have sourced relationships with apitegromab?
apitegromab has dated SEC/FDA relationship records for Scholar Rock Holding Corp.
How many clinical trials involve apitegromab?
BioSniper tracks 5 clinical trials involving apitegromab.