apitegromab
apitegromab: developed by 1 company · 5 clinical trials tracked.
apitegromab evidence translation
What we can confirm
5 tracked trials
What it means
What to watch
Prepared research question
How could apitegromab → SRRK affect its developer, and what evidence supports the link?
Traceable citations · Unknowns marked
See linked entities and source evidence3 indications · 0 study sponsors
Related indications
Study sponsors
No additional listed-company sponsor is linked.
Development Pipeline (1)
| Company | Phase |
|---|---|
| Scholar Rock Holding Corp (SRRK) SMA; Spinal Muscular Atrophy; Facioscapulohumeral Muscular D… | Phase 3 |
Clinical Trials (5)
Expanded Access Protocol of Apitegromab for Patients With Spinal Muscular Atrophy
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter, 52-Week Study Evaluating the Efficacy and Safety of Apitegromab in Participants With Facioscapulohumeral Muscular Dystrophy (FORGE)
Primary endpoint: Assess the efficacy of apitegromab compared with placebo in participants with FSHD
A Phase 2, Double-Blind Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Efficacy, and Safety of Apitegromab in Subjects <2 Years Old With Spinal Muscular Atrophy (SMA)
Primary endpoint: Evaluate the PK of apitegromab in subjects <2 years old with SMA
A Phase 2 Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Apitegromab in Overweight and Obese Adult Subjects
Primary endpoint: Change from Baseline in total Lean Body Mass (kg) at 24 weeks
Phase 3, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Apitegromab (SRK-015) in Patients With Later-Onset Spinal Muscular Atrophy Receiving Background Nusinersen or Risdiplam Therapy
Primary endpoint: Main Efficacy Population: Change from Baseline in Hammersmith Functional Motor Scale Expanded (HFMSE) total score.
Frequently asked questions
Who is developing apitegromab?
apitegromab is being developed by Scholar Rock Holding Corp.
How many clinical trials involve apitegromab?
BioSniper tracks 5 clinical trials involving apitegromab.