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anti-tmprss6 monoclonal antibody disc-3405

Generic: Anti-TMPRSS6 Monoclonal Antibody DISC-3405

anti-tmprss6 monoclonal antibody disc-3405: developed by 1 company · 2 clinical trials tracked.

anti-tmprss6 monoclonal antibody disc-3405 evidence translation

What we can confirm

What it means

Source-backed records connect anti-tmprss6 monoclonal antibody disc-3405 to IRON; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could anti-tmprss6 monoclonal antibody disc-3405 → IRON affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence2 indications · 0 study sponsors

Related indications

Polycythemia Vera (PV); Sickle Cell DiseaseSickle Cell Disease

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
Disc Medicine, Inc. (IRON)
Polycythemia Vera (PV); Sickle Cell Disease
Phase 3
Clinical Trials (2)

A Phase 1b Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DISC-3405 in Participants With Sickle Cell Disease

NCT07187973·Phase 1·IRON
Recruiting

Primary endpoint: Safety and tolerability of DISC-3405 administration in participants with SCD

Interventionalopen24 targetStarted 2026-01Completion 2027-108 sites · United StatesDisc Medicine, Inc

A Phase 2, Open-Label Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of DISC-3405 in Participants With Polycythemia Vera (PV)

NCT06985147·Phase 2·IRON
Active, not recruiting

Primary endpoint: Number of participants with treatment-related adverse events as assessed by CTCAE

Interventionalopen60 targetStarted 2025-08Completion 2029-0215 sites · United StatesDisc Medicine, Inc

Frequently asked questions

Who is developing anti-tmprss6 monoclonal antibody disc-3405?

anti-tmprss6 monoclonal antibody disc-3405 is being developed by Disc Medicine, Inc..

How many clinical trials involve anti-tmprss6 monoclonal antibody disc-3405?

BioSniper tracks 2 clinical trials involving anti-tmprss6 monoclonal antibody disc-3405.