anti-tgf-beta monoclonal antibody sar-439459
anti-tgf-beta monoclonal antibody sar-439459: 2 clinical trials tracked.
anti-tgf-beta monoclonal antibody sar-439459 evidence translation
What we can confirm
2 tracked trials
What it means
What to watch
Prepared research question
What is verified about anti-tgf-beta monoclonal antibody sar-439459, and what remains unknown?
Traceable citations · Unknowns marked
See linked entities and source evidence1 indications · 1 study sponsors
Related indications
Study sponsors
Clinical Trials (2)
A Phase 1b, Single Ascending Dose, Randomized, Double-blind Study to Evaluate the Safety, Tolerability, and Activity of SAR439459 in Adults With Osteogenesis Imperfecta
Primary endpoint: Number of participants with adverse events (AEs)/treatment-emergent adverse events (TEAEs)
Phase 1-2 UMBRELLA Trial Evaluating Isatuximab With or Without Dexamethasone in Combination With Novel Agents Compared to Isatuximab With Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma (RRMM) - Master Protocol
Primary endpoint: Part 1 (dose finding, experimental substudies): Determination of recommended dose of novel agents in combination with isatuximab