Skip to main content

anti-b7-h4/anti-4-1bb bispecific antibody cln-418

Generic: Anti-B7-H4/Anti-4-1BB Bispecific Antibody CLN-418

anti-b7-h4/anti-4-1bb bispecific antibody cln-418: developed by 1 company · 1 clinical trial tracked.

anti-b7-h4/anti-4-1bb bispecific antibody cln-418 evidence translation

What we can confirm

What it means

Source-backed records connect anti-b7-h4/anti-4-1bb bispecific antibody cln-418 to CGEM; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could anti-b7-h4/anti-4-1bb bispecific antibody cln-418 → CGEM affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence1 indications · 1 study sponsors

Related indications

Patients with advanced solid tumors; targets cancers with high B7H4 expression
Development Pipeline (1)
CompanyPhase
Cullinan Therapeutics, Inc. (CGEM)
Patients with advanced solid tumors; targets cancers with hi…
Phase 1/Phase 2
Clinical Trials (1)

A Phase 1 Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CLN-418 in Subjects With Advanced Solid Tumors

NCT05306444·Phase 1·QBIO
Completed

Primary endpoint: Proportion of subjects with dose-limiting toxicity (DLT)

Interventionalopen48 enrolledStarted 2022-05Completion 2024-097 sites · Australia, United StatesHarbour BioMed US, Inc.

Frequently asked questions

Who is developing anti-b7-h4/anti-4-1bb bispecific antibody cln-418?

anti-b7-h4/anti-4-1bb bispecific antibody cln-418 is being developed by Cullinan Therapeutics, Inc..

How many clinical trials involve anti-b7-h4/anti-4-1bb bispecific antibody cln-418?

BioSniper tracks 1 clinical trial involving anti-b7-h4/anti-4-1bb bispecific antibody cln-418.