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alk inhibitor nvl-655

Generic: ALK Inhibitor NVL-655

alk inhibitor nvl-655: developed by 1 company · 3 clinical trials tracked.

alk inhibitor nvl-655 evidence translation

What we can confirm

3 tracked trials

What it means

Source-backed records connect alk inhibitor nvl-655 to NUVL; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could alk inhibitor nvl-655 → NUVL affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence1 indications · 0 study sponsors

Related indications

Locally Advanced Solid Tumor; Non-small Cell Lung Cancer

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
Nuvalent, Inc. (NUVL)
Locally Advanced Solid Tumor; Non-small Cell Lung Cancer
Phase 3
Clinical Trials (3)

Expanded Access Treatment of Neladalkib (NVL-655) in Patients With Advanced ALK+ NSCLC or Other ALK+ Solid Tumors

Available
Expanded Access47 sites · Australia, Canada, France, Italy…Nuvalent Inc.

A Phase 3 Study of the Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor NVL-655 Compared to Alectinib in First-Line Treatment of Patients With ALK-Positive Advanced Non-Small Cell Lung Cancer (ALKAZAR)

NCT06765109·Phase 3·NUVL
Recruiting

Primary endpoint: Progression-free survival (PFS) per blinded independent central review (BICR)

InterventionalRandomizedsingle450 targetStarted 2025-07Completion 2029-1250 sites · Argentina, Australia, Austria, Belgium…Nuvalent Inc.

A Phase 1/2 Study of the Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor NVL-655 in Patients With Advanced NSCLC and Other Solid Tumors (ALKOVE-1)

NCT05384626·Phase 1/Phase 2·NUVL
Recruiting

Primary endpoint: Dose limiting toxicities (DLTs) (Phase 1)

Interventionalopen840 targetStarted 2022-06Completion 2028-0150 sites · Australia, Belgium, Canada, France…Nuvalent Inc.

Frequently asked questions

Who is developing alk inhibitor nvl-655?

alk inhibitor nvl-655 is being developed by Nuvalent, Inc..

How many clinical trials involve alk inhibitor nvl-655?

BioSniper tracks 3 clinical trials involving alk inhibitor nvl-655.