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KARD

Kardigan, Inc.

Biopharma developer (SEC filing verified)·Phase 3·Princeton, NJ, United States·CEO: Mr. Tassos Anastasios E. Gianakakos M.Sc., MBA
Cardiovascular

KARD evidence brief

What we can confirm

BioSniper Score:
9.6 / 10
Market Cap:
$2.02B

What it means

The company data is ready for cross-source review; unsupported conclusions remain unknown.

What to watch

BioSniper Score: 9.6 / 10 · Market Cap: $2.02B
BioSniper AIPage evidence connected

Prepared research question

What matters most for KARD—catalysts, financial risk and supporting evidence?

Run cited research

Traceable citations · Unknowns marked

BioSniper AI · KARD

Kardigan is a clinical-stage precision therapeutics company developing targeted treatments for cardiovascular diseases with no approved therapies, currently advancing three late-stage programs.

Key risk: No revenue yet

9.6/10

BioSniper Score

Based on 2 of 6 signals

Limited data coverage

Market Cap

$2.02B

Cash Runway

—

Lead Asset

—

Next Catalyst

—

Financial data as of Jun 30, 2026.

Tracking 3 clinical trials for Kardigan, Inc..

AI OverviewAI overview is shown in English only.

Kardigan is a clinical-stage precision therapeutics company developing targeted treatments for cardiovascular diseases with no approved therapies, currently advancing three late-stage programs.

  • Kardigan is a clinical-stage precision therapeutics company developing medicines for cardiovascular diseases where no approved treatments exist [sec_mda · as of 2026-08-11].
  • The company has three late-stage programs: Danicamtiv (genetic DCM), Ataciguat (moderate CAVS), and Tonlamarsen (post-hospitalization ASH) [sec_mda · as of 2026-08-11].
  • As of 2026-06-30, Kardigan reported cash & equivalents of $384.0M, net income of -$116.2M, and shareholders' equity of $615.5M [sec].
  • Kardigan has not generated any revenue from product sales and has incurred significant operating losses since inception [sec · filed 2026-06-11].
  • The company anticipates sharing topline data from the Phase 2b portion of the KINSHIP-DCM trial for Danicamtiv in the first half of 2027 [sec · filed 2026-06-11].

What works

  • Kardigan has a substantial cash position of $384.0M as of 2026-06-30, providing a multi-year runway to advance its pipeline [sec].
  • The company targets high-need cardiovascular indications with no approved therapies, potentially creating new standards of care [sec_mda · as of 2026-08-11].
  • Kardigan's management team includes leaders from MyoKardia, indicating experienced leadership in cardiovascular drug development [sec_mda · as of 2026-08-11].

What to weigh

  • Kardigan has not yet generated any revenue from product sales and has incurred significant operating losses, with a net loss of $116.2M for the six months ended June 30, 2026 [sec].
  • The company's business is highly dependent on the success of its three product candidates; failure of any could materially harm the business [sec · filed 2026-06-11].
  • Kardigan will require additional funding to finance operations if its current cash is insufficient, and inability to raise capital could force delays or reductions in programs [sec · filed 2026-06-11].

From the filings

Quoted directly from source documents.

  • Kardigan is a clinical-stage precision therapeutics company developing medicines for cardiovascular diseases with no approved treatments.

    “a clinical-stage precision therapeutics company developing medicines that target the root cause of specific cardiovascular diseases where no approved treatments exist.”

    SEC MD&A · August 11, 2026

  • Kardigan has three late-stage programs: Danicamtiv, Ataciguat, and Tonlamarsen.

    “We have three late-stage programs, Danicamtiv, Ataciguat, and Tonlamarsen, in clinical development for indications for which no approved therapies currently exist.”

    SEC MD&A · August 11, 2026

  • Kardigan has not generated any revenue from product sales and has incurred significant operating losses.

    “Since our inception, we have not generated any revenue from product sales or other sources and have incurred significant operating losses and negative cash flows from our operations.”

    SEC filings · June 11, 2026

  • Kardigan anticipates sharing topline data from the Phase 2b portion of the KINSHIP-DCM trial in the first half of 2027.

    “We anticipate sharing topline data from the Phase 2b portion of theKINSHIP-DCMin the first half of 2027.”

    SEC filings · June 11, 2026

Catalyst timeline

  • 2026-02-13 · Phase 2b/3 trial start for Danicamtiv in genetic DCM — Adaptive, randomized, double-blind, placebo-controlled study to assess efficacy and safety in symptomatic genetic and familial dilated cardiomyopathy.
  • 2026-06-23 · Phase 2b trial start for Tonlamarsen in ASH — Randomized, double-blind, placebo-controlled study to evaluate efficacy and safety in participants with recent hospitalization and acute severe hypertension.
  • 2026-08-26 · Open-label extension study start for Danicamtiv — Long-term safety and efficacy study in adults with symptomatic genetic and familial dilated cardiomyopathy.
Risks & what to watch (3)›

Key risks

  • No revenue yet — Kardigan has not generated any product revenue and relies on funding; net loss of $116.2M as of 2026-06-30 [sec].
  • Pipeline concentration risk — Business depends on success of Danicamtiv, Ataciguat, and Tonlamarsen; failure of any could materially harm the company [sec · filed 2026-06-11].
  • Need for additional funding — If current cash is insufficient, Kardigan will require more capital; inability to raise funds could delay or reduce programs [sec · filed 2026-06-11].

What to watch

  • Topline data from the Phase 2b portion of the KINSHIP-DCM trial for Danicamtiv, expected in the first half of 2027 [sec · filed 2026-06-11].
  • Progress of the Phase 2b trial for Tonlamarsen in post-hospitalization management of acute severe hypertension, started in June 2026 [catalyst].
  • Cash runway and any future financing rounds, given the company's operating losses and reliance on external funding [sec].
  • Regulatory and clinical developments for Ataciguat in moderate calcific aortic valve stenosis [sec · filed 2026-06-11].

Sources: Catalysts · News · SEC filings · SEC MD&A · Generated October 10, 2026 · How we verify sources →

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Evidence & data

Score breakdownBased on 2 of 6 signals · derived from public data

Pipeline inputs are unavailable for this score. It uses only the available signals shown below.

Cash RunwayN/A

Cash runway data unavailable

Financial Health9.7

D/E 0.17 · 0% dilution

Pipeline MaturityN/A

No tracked pipeline phase

Pipeline BreadthN/A

No tracked pipeline candidates

Catalyst MomentumN/A

No upcoming catalysts tracked

Insider Signal9.5

3 buys · 0 sells (180d)

Regulatory

Financials

Frequently asked questions

What is the AI investment thesis for Kardigan, Inc.?

Kardigan is a clinical-stage precision therapeutics company developing targeted treatments for cardiovascular diseases with no approved therapies, currently advancing three late-stage programs.

Who is the CEO of Kardigan, Inc.?

Mr. Tassos Anastasios E. Gianakakos M.Sc., MBA is the chief executive officer of Kardigan, Inc. (KARD).

Where is Kardigan, Inc. headquartered?

Kardigan, Inc. (KARD) is headquartered in Princeton, NJ, United States.

What therapeutic areas does Kardigan, Inc. focus on?

Kardigan, Inc. develops therapies across Cardiovascular.

923 companies304,846 SEC filings22,682 clinical trials100% citation-verification pass rate (7d)How we verify →

The AI overview and BioSniper Score are neutral, data-derived signals built from public SEC filings, ClinicalTrials.gov and FDA records — not investment advice.