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crb-701

Generic: SYS6002·Code: SYS6002

crb-701: developed by 1 company · 2 clinical trials tracked.

crb-701 evidence translation

What we can confirm

What it means

Source-backed records connect crb-701 to CRBP; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could crb-701 → CRBP affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence1 indications · 0 study sponsors

Related indications

Oropharyngeal Carcinoma (OPC); Solid Tumor, Adult

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
Corbus Pharmaceuticals Holdings, Inc. (CRBP)
Oropharyngeal Carcinoma (OPC); Solid Tumor, Adult
Phase 3
Clinical Trials (2)

A Randomized, 2-Arm Study to Evaluate the Efficacy and Safety of CRB-701 Compared With Investigator's Choice of Capecitabine, Cetuximab, or Docetaxel in Participants With Recurrent or Metastatic Oropharyngeal Squamous Cell Carcinoma Previously Treated With Platinum-based Chemotherapy and a PD-(L)1 Inhibitor

NCT07768189·Phase 3·CRBP
Not yet recruiting

Primary endpoint: Objective Response Rate (%)

InterventionalRandomizedsingle260 targetStarted 2026-09Completion 2029-0328 sites · Austria, United Kingdom, United StatesCorbus Pharmaceuticals Inc.

A Phase 1/2 Study to Investigate the Safety, Pharmacokinetics, and Efficacy of CRB-701, an Antibody-drug Conjugate Targeting Nectin-4, in Patients With Advanced Solid Tumors

NCT06265727·Phase 1/Phase 2·CRBP
Recruiting

Primary endpoint: Part A: To confirm the safety and tolerability and determine MTD and PADR for CRB-701

InterventionalRandomizedopen348 targetStarted 2024-04Completion 2027-0141 sites · France, Italy, Moldova, Romania…Corbus Pharmaceuticals Inc.

Frequently asked questions

Who is developing crb-701?

crb-701 is being developed by Corbus Pharmaceuticals Holdings, Inc..

How many clinical trials involve crb-701?

BioSniper tracks 2 clinical trials involving crb-701.